OMICS Analyses in Xenotransplantation: Initial Findings, Key Precautions, and Virus Infections. [PDF]
Denner J.
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Neutralizing Antibodies Against the Porcine Endogenous Retroviruses (PERVs). [PDF]
Ban J, Krabben L, Kaufer BB, Denner J.
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Epigenetic mechanisms of retroviral regulation: a comparative review. [PDF]
Shin SY +3 more
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Genomic Validation of PERV-C-Free Pigs to Support Xenotransplantation. [PDF]
Benjamin NR +6 more
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A study on the transcriptional characteristics of novel HERV gene in the blood of children with Kawasaki disease and its correlation with the disease. [PDF]
Lu Y +10 more
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Engineering Immortalized Bovine Granulosa Cells Using a Triple-Gene Approach: Mutant CDK4, Cyclin D1, and TERT. [PDF]
Bai L +12 more
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Challenges and perspectives in xenoliver research: lessons from decedent and primate models. [PDF]
Hahn Z +3 more
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Diversity and evolutionary history of endogenous retroviruses in the genome of <i>Manis pentadactyla</i>. [PDF]
Zhang T, Xu J, Yang H, Zhou C, Zhang W.
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A newly cloned pig dolichyl-phosphate mannosyltransferase for preventing the transmission of porcine endogenous retrovirus to human cells. [PDF]
ヤマモト, アキ, 山本, 亜紀
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Infection by porcine endogenous retrovirus after islet xenotransplantation in SCID mice
Nature, 2000Animal donors such as pigs could provide an alternative source of organs for transplantation. However, the promise of xenotransplantation is offset by the possible public health risk of a cross-species infection. All pigs contain several copies of porcine endogenous retroviruses (PERV), and at least three variants of PERV can infect human cell lines in
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