Results 161 to 170 of about 7,153 (189)

Porcine Endogenous Retrovirus Transmission Characteristics From a Designated Pathogen-Free Herd

Transplantation Proceedings, 2008
Previously, a strategy for monitoring pigs intended for cell transplantation was developed and successfully applied to several representative herds in New Zealand. A better understanding of porcine viruses' epidemiology in New Zealand has been achieved, and, as a result, a designated pathogen-free (DPF) herd has been chosen as a good candidate for ...
O, Garkavenko, S, Wynyard, D, Nathu, M, Muzina, Z, Muzina, L, Scobie, R D, Hector, M C, Croxson, P, Tan, B R, Elliott   +9 more
openaire   +3 more sources

Detection of porcine endogenous retrovirus in cultures of freshly isolated porcine bone marrow cells

Xenotransplantation, 2003
Abstract: Pigs are under consideration as possible sources of organs for xenotransplantation in humans. The induction of hematopoietic microchimerism through xenotransplantation of source animal hematopoietic cells has been suggested as a means to induce tolerance in potential recipients.
Maritza C, McIntyre, Bhanumathi, Kannan, Gloria I, Solano-Aguilar, Carolyn A, Wilson, Eda T, Bloom, Matiza C, McIntyre   +5 more
openaire   +2 more sources

IN VIVO ANALYSIS OF PORCINE ENDOGENOUS RETROVIRUS EXPRESSION IN TRANSGENIC PIGS

Transplantation, 2001
Xenotransplantation offers a potential solution to the shortage of donor organs for allotransplantation. In vitro studies that demonstrate the transmission of porcine endogenous retroviruses (PERV) from porcine cells to human cells and cell lines have raised concerns regarding the potential transmission of PERV to both xenograft recipients and their ...
G A, Langford, D, Galbraith, A J, Whittam, P, McEwan, X M, Fernández-Suárez, J, Black, A, Shepherd, D, Onions   +7 more
openaire   +2 more sources

A primary screening of porcine endogenous retrovirus in some Chinese pigs

Transplantation Proceedings, 2003
THE CONTINUING shortage of human organs for human transplantation has prompted consideration of animal organs and cells as an alternative tissue source, among which pigs are promising source of xenografts, including fetal pig pancreatic islet cells for insulin-dependent diabetes and neural cells for refractory parkinsonism, as well as extracorporeal ...
L, Zhang, H, Bu, Y, Li, J, Cheng, S, Li, P, Yu   +5 more
openaire   +2 more sources

[Research of porcine endogenous retrovirus in Shaziling pigs].

Yi chuan = Hereditas, 2009
To provide basic parameters of evaluating the biological safety of xenotransplantation from pig to human, ear tissues from 31 individuals were randomly collected from a Shazi Ling pig population. PCR and RT-PCR were performed to detect porcine endogenous retrovirus (PERV) proviral DNA and mRNA respectively.
Xiao-Wei, Xing, Li-Qun, Xue, Sheng-Qiang, Huang, Wei, Wang   +3 more
openaire   +1 more source

Phylogenetic analysis of porcine endogenous retrovirus variation in three Chinese pigs

Transplantation Proceedings, 2004
PCR amplification was performed on genomic DNA extracted from peripheral blood lymphocytes of three species of Chinese pigs (Banna minipig inbreed [BMI], Wu-Zhi-Shan pig [WZSP], and Nei jiang pig [NJP]), using primers corresponding to the highly conserved regions of polymerase (pol) gene.
L, Zhang, P, Yu, S, Li, Y, Li, Y, Zeng, J, Cheng, H, Bu   +6 more
openaire   +2 more sources

[Porcine endogenous retrovirus in Daweizi pigs in Hunan].

Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences, 2013
To detect porcine endogenous retrovirus (PERV) in Daweizi pigs and to provide basic parameters of evaluating the biological safety for xenotransplantation from pigs to humans.Ear tissues from 42 individuals were randomly collected from a Daweizi pig population. PCR and RT-PCR were performed to detect PERV proviral DNA and mRNA respectively.
Xiao-Wei, Xing, Li-Qun, Xue, Zhao-Hui, Mo, Sheng-Qiang, Huang, Wei, Wang   +4 more
openaire   +1 more source

Genetic Prevalence of Porcine Endogenous Retrovirus in Chinese Experimental Miniature Pigs

Transplantation Proceedings, 2011
Pig-to-human xenotransplantation poses the potential risk of interspecies transmission of porcine endogenous retrovirus (PERV). The Chinese experimental miniature pig may be used as a pig-to-human xenograft donor. However, data for the distribution of PERV provirus in genomic DNA and PERV expression at the RNA level for the Chinese experimental ...
G, Liu, Z, Li, M, Pan, M, Ge, Y, Wang, Y, Gao   +5 more
openaire   +2 more sources

Large-scale survey of porcine endogenous retrovirus in Chinese miniature pigs

Comparative Immunology, Microbiology and Infectious Diseases, 2008
We conducted a large-scale survey on the existence and expression status of porcine endogenous retrovirus (PERV) in seven breeds of Chinese miniature pigs. Genotyping of PERV was examined by PCR using type-specific primers according to the env genotyping method. The presence and expression status of viral gag, pol and env genes were further analyzed in
Jianmin, Wu, Yuyuan, Ma, Maomin, Lv, Yubiao, Yang, Yanru, Guo, Xiuling, Yu, Kegong, Tian, Jingang, Zhang   +7 more
openaire   +2 more sources

Porcine endogenous retrovirus (PERV) Integration in the pig genome

2011
absent
Scobie, Linda, Wali, Rashmi, Bauser, Chris, Gaillard, Claire, Blomberg, Jonas, Sperber, Goran, Takeuchi, Yasu   +6 more
openaire   +2 more sources