Results 1 to 10 of about 11,123 (202)

Monitoring for PERV Following Xenotransplantation [PDF]

open access: yesTransplant International
Porcine endogenous retroviruses (PERVs) are integrated in the genome of all pigs. PERV-A, PERV-B and PERV-C can be released as infectious virus particles and PERV-A and PERV-B can infect human cells in culture.
Joachim Denner
doaj   +5 more sources

Reliable Polymerase Chain Reaction Methods for Screening for Porcine Endogenous Retroviruses-C (PERV-C) in Pigs [PDF]

open access: yesViruses
Porcine endogenous retrovirus C (PERV-C) is a gammaretrovirus present in the genome of many, but not all, pigs. It is an ecotropic virus, able to infect only pig cells.
Vasileios G Papatsiros   +2 more
exaly   +4 more sources

Differential resistance to cell entry by porcine endogenous retrovirus subgroup A in rodent species [PDF]

open access: yesRetrovirology, 2007
Background The risk of zoonotic infection by porcine endogenous retroviruses (PERV) has been highlighted in the context of pig-to-human xenotransplantation. The use of receptors for cell entry often determines the host range of retroviruses.
Takeuchi Yasuhiro   +2 more
doaj   +3 more sources

Characterization of porcine endogenous retrovirus insertion in Jeju native pigs and commercial breeds [PDF]

open access: yesAnimal Bioscience
Objective This study aimed to characterize the genomic distribution and amino acid homology of porcine endogenous retrovirus (PERV) subtypes in three pig breeds, Jeju native pigs (JNPs), Duroc, and Landrace.
Seungwon Yoon   +9 more
doaj   +2 more sources

High Prevalence of Recombinant Porcine Endogenous Retroviruses (PERV-A/Cs) in Minipigs: A Review on Origin and Presence

open access: yesViruses, 2021
Minipigs play an important role in biomedical research and they have also been used as donor animals for preclinical xenotransplantations. Since zoonotic microorganisms including viruses can be transmitted when pig cells, tissues or organs are ...
Joachim Denner
exaly   +3 more sources

Equivariant perverse sheaves on Coxeter arrangements and buildings [PDF]

open access: yesÉpijournal de Géométrie Algébrique, 2019
When $W$ is a finite Coxeter group acting by its reflection representation on $E$, we describe the category ${\mathsf{Perv}}_W(E_{\mathbb C}, {\mathcal{H}}_{\mathbb C})$ of $W$-equivariant perverse sheaves on $E_{\mathbb C}$, smooth with respect to the ...
Martin H. Weissman
doaj   +3 more sources

Neutralizing Antibodies Against the Porcine Endogenous Retroviruses (PERVs) [PDF]

open access: yesViruses
Xenotransplantation using pig cells, tissues or organs may be associated with the transmission of porcine zoonotic or xenozoonotic microorganisms. Porcine endogenous retroviruses (PERVs) pose a special risk for xenotransplantation as these viruses can ...
Jinzhao Ban   +3 more
doaj   +2 more sources

Porcine Endogenous Retrovirus (PERV) – Molecular Structure and Replication Strategy in the Context of Retroviral Infection Risk of Human Cells

open access: yesFrontiers in Microbiology, 2018
The xenotransplantation of porcine tissues may help overcome the shortage of human organs for transplantation. However, there are some concerns about recipient safety because the risk of porcine endogenous retrovirus (PERV) transmission to human cells ...
Krzysztof Łopata   +2 more
exaly   +3 more sources

Can Antiretroviral Drugs Be Used to Treat Porcine Endogenous Retrovirus (PERV) Infection after Xenotransplantation?

open access: yesViruses, 2017
Porcine endogenous retroviruses (PERVs) are integrated in the genome of all pigs; they are released as infectious particles, and under certain conditions they can infect human cells. Therefore, they represent a risk when pigs are used as sources of cells,
Joachim Denner
exaly   +3 more sources

Application of Methods Detecting Xenotransplantation-Relevant Viruses for Screening German Slaughterhouse Pigs [PDF]

open access: yesViruses
Detection methods have been developed to prevent transmission of zoonotic or xenozoonotic porcine viruses after transplantation of pig organs or cells to the recipient (xenotransplantation).
Hina Jhelum   +2 more
doaj   +2 more sources

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