Results 31 to 40 of about 11,123 (202)
The article presents the analysis of the PERV retrovirus subtypes A and C frequency in populations of Ukrainian and foreign breed pigs. Different frequencies of the PERV A/C genome presence in animals of the studied breeds were established.
T. M. Ryk
doaj +1 more source
Pig to human xenotransplantation is considered to be a possible approach to alleviate the shortage of human allografts. Porcine endogenous retrovirus (PERV) is the most significant pathogen in xenotransplantation.
Yuyuan Ma +16 more
doaj +1 more source
Genome-wide inactivation of porcine endogenous retroviruses (PERVs) [PDF]
Virally cleansing the pig genome Transplants from pigs could be a solution to a shortage of human organs for transplantation. Unfortunately, porcine endogenous retroviruses (PERVs) are rife in pigs and can be transmitted to humans, risking disease. L. Yang et al.
Yang, Luhan +13 more
openaire +3 more sources
Porcine Endogenous Retroviruses in Xenotransplantation—Molecular Aspects
In the context of the shortage of organs and other tissues for use in human transplantation, xenotransplantation procedures with material taken from pigs have come under increased consideration.
Magdalena C. Kimsa +6 more
doaj +1 more source
Sensitive detection systems for infectious agents in xenotransplantation*
Abstract Xenotransplantation of pig cells, tissues, or organs may be associated with transmission of porcine microorganisms, first of all of viruses, to the transplant recipient, potentially inducing a disease (zoonosis). I would like to define detection systems as the complex of sample generation, sample preparation, sample origin, time of sampling ...
Joachim Denner
wiley +1 more source
Evidence for Microchimerism in Baboon Recipients of Pig Hearts
Xenotransplantation, like allotransplantation, is usually associated with microchimerism, i.e., the presence of cells from the donor in the recipient.
Hina Jhelum +10 more
doaj +1 more source
Twisted geometric Satake equivalence [PDF]
We generalize the classical Satake equivalence as follows. Let k be an algebraically closed field, set O=k[[t]] and F=k((t)). For an almost simple algebraic group G we classify central extensions of G(F) by the multiplicative group.
Finkelberg, Michael, Lysenko, Sergey
core +3 more sources
Previously a strategy for monitoring of pigs intended for cell transplantation was developed and successfully applied to several representative herds in New Zealand.
O. Garkavenko +10 more
doaj +1 more source
Pigs are used as potential donor animals for xenotransplantation. However, porcine endogenous retrovirus (PERV), shown to infect both human and non-human primate (NHP) cells in vitro, presents a risk of transmission to humans in xenotransplantation.
Yoonki Heo +9 more
doaj +1 more source
Gene-modified miniature pigs serve as alternative tissue and organ donors for xenotransplantation to alleviate the shortage of human allogenic organs.
Shuwen Zheng +11 more
doaj +1 more source

