Results 31 to 40 of about 11,123 (202)

Endogenic retroviruses of PERV A/C in genome of Ukrainian pigs and their correlation with the level of fat in carcasses

open access: yesБіологія тварин, 2021
The article presents the analysis of the PERV retrovirus subtypes A and C frequency in populations of Ukrainian and foreign breed pigs. Different frequencies of the PERV A/C genome presence in animals of the studied breeds were established.
T. M. Ryk
doaj   +1 more source

Screening and Identification of the First Non-CRISPR/Cas9-Treated Chinese Miniature Pig With Defective Porcine Endogenous Retrovirus pol Genes

open access: yesFrontiers in Immunology, 2022
Pig to human xenotransplantation is considered to be a possible approach to alleviate the shortage of human allografts. Porcine endogenous retrovirus (PERV) is the most significant pathogen in xenotransplantation.
Yuyuan Ma   +16 more
doaj   +1 more source

Genome-wide inactivation of porcine endogenous retroviruses (PERVs) [PDF]

open access: yesScience, 2015
Virally cleansing the pig genome Transplants from pigs could be a solution to a shortage of human organs for transplantation. Unfortunately, porcine endogenous retroviruses (PERVs) are rife in pigs and can be transmitted to humans, risking disease. L. Yang et al.
Yang, Luhan   +13 more
openaire   +3 more sources

Porcine Endogenous Retroviruses in Xenotransplantation—Molecular Aspects

open access: yesViruses, 2014
In the context of the shortage of organs and other tissues for use in human transplantation, xenotransplantation procedures with material taken from pigs have come under increased consideration.
Magdalena C. Kimsa   +6 more
doaj   +1 more source

Sensitive detection systems for infectious agents in xenotransplantation*

open access: yesXenotransplantation, EarlyView., 2020
Abstract Xenotransplantation of pig cells, tissues, or organs may be associated with transmission of porcine microorganisms, first of all of viruses, to the transplant recipient, potentially inducing a disease (zoonosis). I would like to define detection systems as the complex of sample generation, sample preparation, sample origin, time of sampling ...
Joachim Denner
wiley   +1 more source

Evidence for Microchimerism in Baboon Recipients of Pig Hearts

open access: yesViruses, 2023
Xenotransplantation, like allotransplantation, is usually associated with microchimerism, i.e., the presence of cells from the donor in the recipient.
Hina Jhelum   +10 more
doaj   +1 more source

Twisted geometric Satake equivalence [PDF]

open access: yes, 2009
We generalize the classical Satake equivalence as follows. Let k be an algebraically closed field, set O=k[[t]] and F=k((t)). For an almost simple algebraic group G we classify central extensions of G(F) by the multiplicative group.
Finkelberg, Michael, Lysenko, Sergey
core   +3 more sources

Porcine Endogenous Retrovirus (PERV) and its Transmission Characteristics: A Study of the New Zealand Designated Pathogen-Free Herd

open access: yesCell Transplantation, 2008
Previously a strategy for monitoring of pigs intended for cell transplantation was developed and successfully applied to several representative herds in New Zealand.
O. Garkavenko   +10 more
doaj   +1 more source

Detection of Pig Cells Harboring Porcine Endogenous Retroviruses in Non-Human Primate Bladder After Renal Xenotransplantation

open access: yesViruses, 2019
Pigs are used as potential donor animals for xenotransplantation. However, porcine endogenous retrovirus (PERV), shown to infect both human and non-human primate (NHP) cells in vitro, presents a risk of transmission to humans in xenotransplantation.
Yoonki Heo   +9 more
doaj   +1 more source

Efficient and Safe Editing of Porcine Endogenous Retrovirus Genomes by Multiple-Site Base-Editing Editor

open access: yesCells, 2022
Gene-modified miniature pigs serve as alternative tissue and organ donors for xenotransplantation to alleviate the shortage of human allogenic organs.
Shuwen Zheng   +11 more
doaj   +1 more source

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