Results 21 to 30 of about 11,123 (202)
Characterization of porcine endogenous retrovirus expression in neonatal and adult pig pancreatic islets [PDF]
, 2017 BACKGROUND: Pig islets represent an alternative to the current modes of treatment for patients with diabetes. However, the concerns over pathogen transmission including that of PERV limit their immediate, widespread usage in humans.
Akiyoshi +36 more
core +1 more source
Scientific Reports, 2020 Several xenogenic cell-based therapeutic products are currently under development around the world for the treatment of human diseases. Porcine islet cell products for treating human diabetes are a typical example.
Ken Kono +5 more
doaj +1 more source
Assessment of porcine endogenous retrovirus transmission across an alginate barrier used for the encapsulation of porcine islets [PDF]
, 2018 BACKGROUND: Subcutaneous implantation of a macroencapsulated patch containing human allogenic islets has been successfully used to alleviate type 1 diabetes mellitus (T1DM) in a human recipient without the need for immunosuppression.
Crossan, Claire +4 more
core +1 more source
First virological and pathological study of Göttingen Minipigs with Dippity Pig Syndrome (DPS).
PLoS ONE, 2023 Dippity Pig Syndrome (DPS) is a well-known but rare complex of clinical signs affecting minipigs, which has not been thoroughly investigated yet. Clinically affected animals show acute appearance of red, exudating lesions across the spine.
Hina Jhelum +13 more
doaj +1 more source
Modules over the small quantum group and semi-infinite flag manifold [PDF]
, 2005 We develop a theory of perverse sheaves on the semi-infinite flag manifold $G((t))/N((t))\cdot T[[t]]$, and show that the subcategory of Iwahori-monodromy perverse sheaves is equivalent to the regular block of the category of representations of the small
Arkhipov, S. +4 more
core +4 more sources
Microlocal sheaves and quiver varieties [PDF]
, 2015 We relate Nakajima Quiver Varieties (or, rather, their multiplicative version) with moduli spaces of perverse sheaves. More precisely, we consider a generalization of the concept of perverse sheaves: microlocal sheaves on a nodal curve X.
Bezrukavnikov, Roman, Kapranov, Mikhail
core +3 more sources
Copy Number and Prevalence of Porcine Endogenous Retroviruses (PERVs) in German Wild Boars
Viruses, 2020 Porcine endogenous retroviruses (PERVs) are integrated in the genome of pigs and are transmitted like cellular genes from parents to the offspring. Whereas PERV-A and PERV-B are present in all pigs, PERV-C was found to be in many, but not all pigs.
Luise Krüger +5 more
doaj +1 more source
, 2012 We prove an analogue of Koszul duality for category $\mathcal{O}$ of a reductive group $G$ in positive characteristic $\ell$ larger than 1 plus the number of roots of $G$. However there are no Koszul rings, and we do not prove an analogue of the Kazhdan--
Riche, Simon +2 more
core +4 more sources
Cell Transplantation, 2004 The discovery of porcine endogenous retroviruses (PERV) has raised concerns regarding the safety of porcine xenotransplantation. However, transmission of PERV had not been observed in humans exposed to porcine tissue.
Brice W. Mckane +5 more
doaj +1 more source
Genomic presence of recombinant porcine endogenous retrovirus in transmitting miniature swine
Virology Journal, 2006 The replication of porcine endogenous retrovirus (PERV) in human cell lines suggests a potential infectious risk in xenotransplantation. PERV isolated from human cells following cocultivation with porcine peripheral blood mononuclear cells is a ...
Wilkinson Robert +2 more
doaj +1 more source