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Porcine Epidemic Diarrhea Virus: Etiology, Epidemiology, Antigenicity, and Control Strategies in China

Animals
Porcine epidemic diarrhea virus (PEDV) is a porcine enteric coronavirus, which is one of the main causative agents of porcine epidemic diarrhea (PED), with 100% morbidity and 80–100% mortality in neonatal piglets.
Jianlin Lei, Yongqiang Miao, Wenrui Bi, Chaohui Xiang, Wei Li, Riteng Zhang, Qian Li, Zengqi Yang   +7 more
doaj   +2 more sources

Antiviral activity of cathelicidins against porcine epidemic diarrhea virus (PEDV): Mechanisms, and efficacy. [PDF]

Virus Res
Porcine epidemic diarrhea virus (PEDV) is a harmful coronavirus infecting pigs, which is resulting in substantial financial losses in the global pig industry.
Pashaie F, Hoornweg TE, Bikker FJ, Veenendaal T, Broere F, Veldhuizen EJA.   +5 more
europepmc   +4 more sources

Phylogenetic Analysis of Porcine Epidemic Diarrhea Virus (PEDV) during 2020-2022 and Isolation of a Variant Recombinant PEDV Strain. [PDF]

Int J Mol Sci
Porcine epidemic diarrhea (PED) is an acute, highly contagious, and infectious disease caused by porcine epidemic diarrhea virus (PEDV). PEDV can affect pigs of all ages, with 50~100% mortality in neonatal piglets and substantial economic losses in the ...
Peng Q, Fu P, Zhou Y, Lang Y, Zhao S, Wen Y, Wang Y, Wu R, Zhao Q, Du S, Cao S, Huang X, Yan Q.   +12 more
europepmc   +2 more sources

Development of a multiplex qRT-PCR assay for the detection of porcine epidemic diarrhea virus, porcine transmissible gastroenteritis virus and porcine Deltacoronavirus

Frontiers in Veterinary Science, 2023
Currently, porcine coronaviruses are prevalent in pigs, and due to the outbreak of COVID-19, porcine coronaviruses have become a research hotspot.
Yan Li, Jia-Wei Niu, Xia Zhou, Pin-Pin Chu, Kun-Li Zhang, Hong-Chao Gou, Dong-Xia Yang, Jian-Feng Zhang, Chun-Ling Li, Ming Liao, Ming Liao, Shao-Lun Zhai   +11 more
doaj   +1 more source

Genetic characterization and phylogenetic analysis of porcine epidemic diarrhea virus in Guangdong, China, between 2018 and 2019.

PLoS ONE, 2021
Porcine epidemic diarrhea virus (PEDV), a leading cause of piglet diarrhea outbreaks, poses a significant danger to the swine industry. The aim of this study was to investigate the epidemic characteristics of PEDV that was circulating in Guangdong ...
Feng Wen, Jing Yang, Anqi Li, Zhonggui Gong, Lulu Yang, Qing Cheng, Congying Wang, Mengmeng Zhao, Sheng Yuan, Yao Chen, Saeed El-Ashram, Yong Li, Hai Yu, Jinyue Guo, Shujian Huang   +14 more
doaj   +1 more source

Porcine Epidemic Diarrhea Virus (PEDV) ORF3 Interactome Reveals Inhibition of Virus Replication by Cellular VPS36 Protein [PDF]

Viruses, 2019
Yodying Yingchutrakul, Anan Jongkaewwattana, Challika Kaewborisuth   +2 more
exaly   +2 more sources

Oral administration of inactivated porcine epidemic diarrhea virus activate DCs in porcine Peyer’s patches

BMC Veterinary Research, 2018
Background Peyer’s patches (PPs) can be considered as the immune site of the intestine. Within PPs, Dendritic cells (DCs) can uptake antigens from the gut lumen by extending dendrites into epithelium, and process it and then present to lymphocytes, which
Chen Yuan, En Zhang, Lulu Huang, Jialu Wang, Qian Yang   +4 more
doaj   +1 more source

Adenovirus vector-mediated single chain variable fragments target the nucleocapsid protein of porcine epidemic diarrhea virus and protect against viral infection in piglets

Frontiers in Immunology, 2023
Porcine epidemic diarrhea virus (PEDV) mainly infects the intestinal epithelial cells of pigs, causing porcine epidemic diarrhea (PED). In particular, the virus causes severe diarrhea, dehydration, and death in neonatal piglets.
Fengqing Wang, Fengqing Wang, Qing Zhang, Fanqing Zhang, En Zhang, Mei Li, Shiwei Ma, Jianming Guo, Zhibiao Yang, Jianguo Zhu   +9 more
doaj   +1 more source

Recombinant Chimeric Transmissible Gastroenteritis Virus (TGEV) - Porcine Epidemic Diarrhea Virus (PEDV) Virus Provides Protection against Virulent PEDV. [PDF]

Viruses, 2019
Porcine epidemic diarrhea virus (PEDV) is an enteric coronavirus causing high morbidity and mortality in porcine herds worldwide. Although both inactivated and live attenuated vaccines have been extensively used, the emergence of highly virulent strains ...
Pascual-Iglesias A, Sanchez CM, Penzes Z, Sola I, Enjuanes L, Zuñiga S.   +5 more
europepmc   +2 more sources

Molecular characteristics of a novel recombinant of porcine epidemic diarrhea virus. [PDF]

, 2019
Porcine epidemic diarrhea (PED) is a contagious viral disease in pigs, caused by the coronavirus porcine epidemic diarrhea virus (PEDV). PEDV infection results in significant mortality in piglets in unvaccinated herds.
Titov, Ilya, Malogolovkin, Alexander, Nefedeva, Mariia   +2 more
core   +1 more source