Porcine lymphotropic herpesviruses – a new threat to domestic pigs in Croatia
Porcine lymphotropic herpesviruses 1, 2 and 3 (PLHV-1, PLHV-2 and PLHV-3) are DNA viruses belonging to the genus Macavirus and the subfamily Gammaherpesvirinae within the family Herpesviridae. PLHV was detected in domestic pigs in Germany in 1999, with subsequent outbreaks in Spain, Brazil, Italy and Ireland, which was the trigger for our preliminary ...
Jelena Prpic, Lorena Jemeršić
exaly +5 more sources
Porcine Gammaherpesviruses in Italian Commercial Swine Population: Frequent but Harmless [PDF]
Differently from alpha- and betaherpesviruses affecting swine, interest in the recently discovered Suid gammaherpesvirus 3, Suid gammaherpesvirus 4, and Suid gammaherpesvirus 5, also known as porcine lymphotropic herpesviruses (PLHV-1, PLHV-2, and PLHV-3)
Giovanni Franzo +7 more
doaj +5 more sources
Porcine Lymphotropic Herpesvirus (PLHV) Was Not Transmitted During Transplantation of Genetically Modified Pig Hearts into Baboons [PDF]
Porcine lymphotropic herpesviruses -1, -2, and -3 (PLHV-1, PLHV-2, and PLHV-3) are gammaherpesviruses that are widespread in pigs. These viruses are closely related to the human pathogens Epstein–Barr virus (EBV) and Kaposi sarcoma-associated ...
Jan-Michaél Abicht +2 more
exaly +5 more sources
Virus Safety of Xenotransplantation
The practice of xenotransplantation using pig islet cells or organs is under development to alleviate the shortage of human donor islet cells or organs for the treatment of diabetes or organ failure.
Joachim Denner
exaly +3 more sources
Patterns of human and porcine gammaherpesvirus-encoded BILF1 receptor endocytosis [PDF]
Background The viral G-protein-coupled receptor (vGPCR) BILF1 encoded by the Epstein–Barr virus (EBV) is an oncogene and immunoevasin and can downregulate MHC-I molecules at the surface of infected cells.
Maša Mavri +6 more
doaj +2 more sources
Xenoperfusion-The Transformative Role of Machine Perfusion in Xenotransplantation. [PDF]
ABSTRACT Recent advances in xenotransplantation have gained substantial public and clinical attention as genetically modified porcine organs are now being transplanted into living human recipients. While only case reports have been published to date, the first clinical trials for kidney xenotransplantation are now ongoing.
Huwyler F +3 more
europepmc +2 more sources
Porcine cytomegalovirus: A very unwelcome stowaway. [PDF]
Xenotransplantation, Volume 29, Issue 3, May/June 2022.
Mueller NJ.
europepmc +2 more sources
Global Consultation for Clinical Xenotransplantation: International Xenotransplantation Association Consensus and Communiqué Update. [PDF]
ABSTRACT Xenotransplantation has entered a phase of accelerated clinical translation, necessitating renewed international consensus on governance, ethics, safety, and regulatory oversight. In September 2025, the International Xenotransplantation Association (IXA), in partnership with The Transplantation Society (TTS) and with engagement from the World ...
Hawthorne WJ +25 more
europepmc +2 more sources
Bovine gammaherpesvirus 6 (BoGHV6), formerly known as bovine lymphotropic virus, belongs to the genus Macavirus, which includes the porcine lymphotropic herpesviruses (PLHV) and members collectively referred to as malignant catarrhal fever virus (MVFV ...
Mariana Motta de Castro +8 more
doaj +1 more source
Viruses in sanctuary chimpanzees across Africa
Abstract Infectious disease is a major concern for both wild and captive primate populations. Primate sanctuaries in Africa provide critical protection to thousands of wild‐born, orphan primates confiscated from the bushmeat and pet trades. However, uncertainty about the infectious agents these individuals potentially harbor has important implications ...
Emily Dunay +9 more
wiley +1 more source

