Results 21 to 30 of about 115,012 (103)

Virological and Parasitological Characterization of Mini-LEWE Minipigs Using Improved Screening Methods and an Overview of Data on Various Minipig Breeds

Microorganisms, 2021
Minipigs play an important role in biomedical research and have also been used as donor animals in xenotransplantation. To serve as a donor in xenotransplantation, the animals must be free of potential zoonotic viruses, bacteria and parasites.
Sabrina Halecker, Julia Metzger, Christina Strube, Ludwig Krabben, Benedikt Kaufer, Joachim Denner   +5 more
doaj   +1 more source

Xenotransplantation of pig islet cells: Potential adverse impact of virus infections on their functionality and insulin production

, 2023
Xenotransplantation, Volume 30, Issue 2, March/April 2023.
Joachim Denner
wiley   +1 more source

Development of a TaqMan Based Real‐Time Fluorescent Quantitative PCR Assay for Detection of Porcine Cytomegalovirus in Semen

BioMed Research International, Volume 2020, Issue 1, 2020., 2020
This study described a TaqMan based real‐time fluorescent quantitative PCR (qPCR) method to detect porcine cytomegalovirus (PCMV) infection, targeting the conserved region of the DNA polymerase (DPOL) gene. The standard curve showed a linear regression relationship with a coefficient of 0.999 and a slope of y = −3.249x + 38.958 corresponding to the ...
Rujing Chen, Qiuyong Chen, Xuemin Wu, Yongliang Che, Chenyan Wang, Longbai Wang, Shan Yan, Lunjiang Zhou, Pengjun Shi   +8 more
wiley   +1 more source

Characterization of the DNA polymerase loci of the novel porcine lymphotropic herpesviruses 1 and 2 in domestic and feral pigs

Journal of General Virology, 1999
Two novel porcine gammaherpesviruses, porcine lymphotropic herpesviruses 1 and 2 (PLHV-1 and -2), have been detected by amplification of short DNA polymerase (DPOL) sequences from blood and spleen of domestic pigs while searching for unknown herpesviruses in pigs as possible risk factors in xenotransplantation.
Sven, Ulrich, Michael, Goltz, Bernhard, Ehlers   +2 more
openaire   +2 more sources

Tales from the crypt and coral reef: the successes and challenges of identifying new herpesviruses using metagenomics. [PDF]

, 2015
Herpesviruses are ubiquitous double-stranded DNA viruses infecting many animals, with the capacity to cause disease in both immunocompetent and immunocompromised hosts.
Charlotte J. Houldcroft, Houldcroft, CJ, Breuer, J, Judith Breuer   +3 more
core   +2 more sources

Distribution of Porcine Cytomegalovirus in Infected Donor Pigs and in Baboon Recipients of Pig Heart Transplantation

Viruses, 2018
The porcine cytomegalovirus (PCMV) is a herpesvirus that may pose a risk for xenotransplantation using pig cells, tissues, or organs. Here, three orthotopic pig heart transplantations into baboons were studied.
Uwe Fiebig, Jan-Michael Abicht, Tanja Mayr, Matthias Längin, Andrea Bähr, Sonja Guethoff, Almuth Falkenau, Eckhard Wolf, Bruno Reichart, Tomoyuki Shibahara, Joachim Denner   +10 more
doaj   +1 more source

Production and characterisation of acellular porcine pulmonary heart valve conduits [PDF]

, 2011
Cardiac valve replacement is the second most common heart operation. Currently available replacement heart valves all have limitations. This study aimed to produce and characterise a decellularised, biocompatible porcine pulmonary root conduit for use ...
Luo, Ji
core   +6 more sources

Dominant-Negative Proteins in Herpesviruses - From Assigning Gene Function to Intracellular Immunization [PDF]

, 2009
Investigating and assigning gene functions of herpesviruses is a process, which profits from consistent technical innovation. Cloning of bacterial artificial chromosomes encoding herpesvirus genomes permits nearly unlimited possibilities in the ...
Christian A. Mohr, Ulrich Koszinowski, Mühlbach, Hermine, Koszinowski, Ulrich H., Zsolt Ruzsics, Christian Mohr, Mohr, Christian A., Ruzsics, Zsolt, Hermine Mühlbach, Ulrich H. Koszinowski   +9 more
core   +1 more source

DataSheet_1_Epstein-Barr Virus-Encoded BILF1 Orthologues From Porcine Lymphotropic Herpesviruses Display Common Molecular Functionality.docx

, 2022
Infection of immunosuppressed transplant patients with the human γ-herpesvirus Epstein-Barr virus (EBV) is associated with post-transplant lymphoproliferative disease (PTLD), an often fatal complication.
Mette M. Rosenkilde (205579), Christene A. Huang (12709777), Jianmin Zuo (190715), Judith Breuer (195563), Valentina Kubale (12754868), Maša Mavri (12754865), Bernhard Ehlers (80336), Toni Petan (148781), Daniel P. Depledge (7865552), Eva Jarc Jovičić (12754871), Katja Spiess (8799113), Milka Vrecl (662594), Michael A. Jarvis (9918298)   +12 more
core   +1 more source

Abstract Book for the 27th Congress of the European Hematology Association

, 2022
HemaSphere, Volume 6, Issue S3, Page 1-4130, June 2022.
wiley   +1 more source