Porcine Lymphotropic Herpesviruses (PLHVs) and Xenotranplantation [PDF]
Viruses, 2021 Porcine lymphotropic herpesviruses -1, -2 and -3 (PLHV-1, PLHV-2 and PLHV-3) are gammaherpesviruses which are widespread in pigs. They are closely related to the Epstein–Barr virus (EBV) and Kaposi sarcoma herpesvirus, both of which cause severe diseases in humans.
Joachim Denner, Denner Joachim
exaly +7 more sources
Epstein-Barr Virus-Encoded BILF1 Orthologues From Porcine Lymphotropic Herpesviruses Display Common Molecular Functionality [PDF]
Frontiers in Endocrinology, 2022 Infection of immunosuppressed transplant patients with the human γ-herpesvirus Epstein-Barr virus (EBV) is associated with post-transplant lymphoproliferative disease (PTLD), an often fatal complication. Immunosuppressed miniature pigs infected with γ-herpesvirus porcine lymphotropic herpesvirus 1 (PLHV1) develop a similar disease, identifying pigs as ...
Jianmin Zuo +2 more
exaly +9 more sources
Porcine Circoviruses and Herpesviruses Are Prevalent in an Austrian Game Population [PDF]
Pathogens, 2022 During the annual hunt in a privately owned Austrian game population in fall 2019 and 2020, 64 red deer (Cervus elaphus), 5 fallow deer (Dama dama), 6 mouflon (Ovis gmelini musimon), and 95 wild boars (Sus scrofa) were shot and sampled for PCR testing ...
Angelika Auer +2 more
exaly +4 more sources
Porcine cytomegalovirus: A very unwelcome stowaway. [PDF]
Xenotransplantation, 2022 Xenotransplantation, Volume 29, Issue 3, May/June 2022.
Mueller NJ.
europepmc +2 more sources
Xenoperfusion-The Transformative Role of Machine Perfusion in Xenotransplantation. [PDF]
XenotransplantationABSTRACT Recent advances in xenotransplantation have gained substantial public and clinical attention as genetically modified porcine organs are now being transplanted into living human recipients. While only case reports have been published to date, the first clinical trials for kidney xenotransplantation are now ongoing.
Huwyler F +3 more
europepmc +2 more sources
Porcine lymphotropic herpesviruses – a new threat to domestic pigs in Croatia
Veterinarska StanicaPorcine lymphotropic herpesviruses 1, 2 and 3 (PLHV-1, PLHV-2 and PLHV-3) are DNA viruses belonging to the genus Macavirus and the subfamily Gammaherpesvirinae within the family Herpesviridae. PLHV was detected in domestic pigs in Germany in 1999, with subsequent outbreaks in Spain, Brazil, Italy and Ireland, which was the trigger for our preliminary ...
Jelena Prpic, Lorena Jemeršić
exaly +3 more sources
First virological and pathological study of Göttingen Minipigs with Dippity Pig Syndrome (DPS). [PDF]
PLoS One, 2023 Dippity Pig Syndrome (DPS) is a well-known but rare complex of clinical signs affecting minipigs, which has not been thoroughly investigated yet. Clinically affected animals show acute appearance of red, exudating lesions across the spine.
Jhelum H +13 more
europepmc +3 more sources
Metagenomic analysis fecal microbiota of dysentery-like diarrhoea in a pig farm using next-generation sequencing. [PDF]
Front Vet Sci, 2023 Porcine enteric diseases including swine dysentery involves a wide range of possible aetiologies and seriously damages the intestine of pigs of all ages.
Chen X, Guo Q, Li YY, Song TY, Ge JQ.
europepmc +2 more sources
Comprehensive Protocols for Detecting Xenotransplantation-Relevant Viruses. [PDF]
Methods ProtocXenotransplantation using pig cells, tissues, or organs is advancing toward clinical application to address the shortage of human donor organs for treating organ failure.
Jhelum H, Kaufer BB, Denner J.
europepmc +2 more sources
Patterns of human and porcine gammaherpesvirus-encoded BILF1 receptor endocytosis. [PDF]
Cell Mol Biol Lett, 2023 Background The viral G-protein-coupled receptor (vGPCR) BILF1 encoded by the Epstein–Barr virus (EBV) is an oncogene and immunoevasin and can downregulate MHC-I molecules at the surface of infected cells.
Mavri M +6 more
europepmc +2 more sources