MultiBac: expanding the research toolbox for multiprotein complexes [PDF]
This article is made available for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source.
Berger, Imre +3 more
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Epidemics to eradication: the modern history of poliomyelitis [PDF]
Poliomyelitis has afflicted humankind since antiquity, and for nearly a century now, we have known the causative agent, poliovirus. This pathogen is an enterovirus that in recent history has been the source of a great deal of human suffering.
Nidia H De Jesus
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Detection of Porcine Teschovirus and Enterovirus Type II by Reverse Transcription–Polymerase Chain Reaction [PDF]
Porcine enteroviruses (PEVs) have been recognized as the causative agents of various clinical manifestations such as fertility disorders, neurological defects, and dermal lesions in pigs. Currently, the diagnosis of PEV infection is carried out by virus isolation, which although useful, is labor- and time-intensive. The present investigation describes
Joseph M, Palmquist +4 more
openaire +2 more sources
A distribution of porcine teschovirus (PTV) antigens in pigs naturally infected with PTV is presented using the method of immunohistochemical examination. In the nervous system, PTV antigens were found in the cytoplasm of neuronal cells and glial cells distributed in the spinal ventral horn and brain stem, and also in the cytoplasm of ganglion cells in
Manabu, Yamada +8 more
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The Avian Encephalomyelitis Virus (AEV) 5’ Untranslated Region Contains an IRES with Similarity to the Hepatitis C Virus IRES [PDF]
Cap-independent internal initiation of protein synthesis has been shown to occur on a number of viral and cellular mRNAs. Initiation of protein synthesis is directed by an internal ribosome entry site (IRES) element within the 5’ untranslated region (UTR)
M Bakhshesh, L Roberts, G J Belsham
doaj +2 more sources
Characterization of strain PTV-2 USA/IA65463/2014 and strain PTV-11 USA/IA09592/2013 of Teschovirus A: Experimental inoculation, distribution of nucleic acids and development of Teschovirus encephalomyelitis [PDF]
Teschovirus A (previously Porcine teschovirus; PTV) is the etiologic agent of Teschovirus encephalomyelitis (TE). Historically, PTV-1 has been recognized as one of the most pathogenic serotypes, although other serotypes have been described to cause TE ...
Matias Ferreyra, Franco S.
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Investigating the functionality of an OCT4-short response element in human induced pluripotent stem cells. [PDF]
Pluripotent stem cells offer great therapeutic promise for personalized treatment platforms for numerous injuries, disorders, and diseases. Octamer-binding transcription factor 4 (OCT4) is a key regulatory gene maintaining pluripotency and self-renewal ...
Awe, Jason P +9 more
core +3 more sources
Development of a Human Cytomegalovirus (HCMV)-Based Therapeutic Cancer Vaccine Uncovers a Previously Unsuspected Viral Block of MHC Class I Antigen Presentation [PDF]
Human cytomegalovirus (HCMV) induces a uniquely high frequency of virus-specific effector/memory CD8+ T-cells, a phenomenon termed “memory inflation”.
Abate +109 more
core +1 more source
Summary Duckweeds (Lemnaceae) have excellent potential for fundamental and applied research due to ease of cultivation, small size, and continuous fast clonal growth. However, their usage as model organisms and platforms for biotechnological applications is often limited by the lack of universal genetic manipulation methods necessary for transgene ...
Verónica Barragán‐Borrero +12 more
wiley +1 more source
Unique Characteristics of a Picornavirus Internal Ribosome Entry Site from the Porcine Teschovirus-1 Talfan [PDF]
ABSTRACT The teschoviruses constitute a recently defined picornavirus genus. Most of the genome sequence of the porcine teschovirus-1 (PTV) Talfan and several other strains is known. We now demonstrate that initiation of protein synthesis occurs at nucleotide (nt) 412 on the PTV Talfan RNA and that nt 1 to 405 contains an internal ribosome ...
Kaku, Yoshihiro +3 more
openaire +3 more sources

