Results 91 to 100 of about 759,323 (315)

Nuclear magnetic resonance cryoporometry [PDF]

, 2008
Nuclear Magnetic Resonance (NMR) cryoporometry is a technique for non-destructively determining pore size distributions in porous media through the observation of the depressed melting point of a confined liquid.
Webber, J. Beau W., Strange, John H., Strange, J H, Webber, Beau, Mitchell, J., Mitchell, J   +5 more
core   +1 more source

Inactivation of Mechanically Activated Piezo1 Ion Channels Is Determined by the C-Terminal Extracellular Domain and the Inner Pore Helix

Cell Reports, 2017
Piezo proteins form mechanically activated ion channels that are responsible for our sense of light touch, proprioception, and vascular blood flow. Upon activation by mechanical stimuli, Piezo channels rapidly inactivate in a voltage-dependent manner ...
Jason Wu, Michael Young, Amanda H. Lewis, Ashley N. Martfeld, Breanna Kalmeta, Jörg Grandl   +5 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Pore-filling and snap-off events superimposed on a pore-throat network extracted from the segmented pore space

, 2019
This movie shows a pore-throat network extracted from the segmented pore space of a Ketton limestone sample. Here, pores are shown as spheres and throats as tubes connecting adjacent pores.
Kamaljit Singh (3345224)
core   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Virus-sized colloid transport in a single pore: Model development and sensitivity analysis

, 2014
A mathematical model is developed to simulate the transport and deposition of virus-sized colloids in a cylindrical pore throat considering various processes such as advection, diffusion, colloid–collector surface interactions and hydrodynamic wall ...
Seetha, N., Raoof, Amir, Seetha, N, Mohan Kumar, M.S, Hassanizadeh, S.M., Raoof, A., Mohan Kumar, M.S., Majid Hassanizadeh, S   +7 more
core   +1 more source

Phase field simulation of grain growth in Al2O3-based composite ceramic cutting tool materials containing second phase nanoparticles and pores

Materials Research Express, 2020
A phase field model was established to simulate the grain growth of Al _2 O _3 -based composite ceramic tool materials containing second phase nanoparticles and pores.
Youxin Zhou, Bin Peng
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Nanoindentation-Induced Deformation Mechanisms in Sintered Silver: A Multiscale Study Combining Experimental and Molecular Dynamics Simulations

Crystals
Sintered silver, widely used in WBG electronic device packaging for its excellent electrothermal properties and high-temperature stability, faces challenges in macroscopic mechanical behavior and reliability due to porosity, especially for pressureless ...
Yiping Sun, Xinyue Wang, Haixue Chen, Pan Liu   +3 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source