Results 101 to 110 of about 759,323 (315)
Reactive/Adsorptive transport in (partially-) saturated porous media: from pore scale to core scale
Pore-scale modeling provides opportunities to study transport phenomena in fundamental ways because detailed information is available at the microscopic pore scale. This offers the best hope for bridging the traditional gap that exists between pore scale
Raoof, A. +2 more
core
High-resolution pore-water sampling with a gel sampler [PDF]
Sediment pore-water profiles were sampled at high resolution (millimeter scale) with a polyacrylamide gel probe. This simple procedure involves inserting a 1-mm-thick gel held in a plastic probe into sediment. The gel reaches diffusive equilibrium in
Krom, M. D. +4 more
core
Nuclear mRNA export is a crucial step in eukaryotic gene expression, which is in yeast coupled to cotranscriptional messenger ribonucleoprotein particle ( mRNP) assembly and surveillance.
Attila Rácz +17 more
core +1 more source
Salmonella spp. is an important foodborne agent of salmonellosis, whose sources in humans often include products of avian origin. The control of this bacterium is difficult especially when Salmonella spp. is organized into biofilms.
Belchiolina Beatriz Fonseca +8 more
doaj +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Free energy analysis of membrane pore formation process in the presence of multiple melittin peptides [PDF]
Understanding the molecular mechanism underlying pore formation in lipid membranes by antimicrobial peptides is of great importance in biological sciences as well as in drug design applications. Melittin has been widely studied as a pore forming peptide,
Shinoda, Wataru +2 more
core +1 more source
A facile way of controlling capillary condensation: particle-based crystal
To demonstrate a facile method to control capillary condensation via the design of confined geometric structures, we use a particle self-assembly technique to fabricate porous materials with well-defined pore sizes.
Shichao Jiao, Joseph J McCarthy
doaj +1 more source
Fusaricidin-Type Compounds Create Pores in Mitochondrial and Plasma Membranes of Mammalian Cells
Fusaricidins and related LI-F compounds are effective bactericides and fungicides. Recently, we have found that they are highly toxic to mammalian cells. Here, we studied the effect of fusaricidin-type compounds (FTCs) on the membranes of mammalian cells.
Raimo Mikkola +4 more
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source

