Results 61 to 70 of about 421,042 (302)

Investigation of nonlinear wave-induced seabed response around mono-pile foundation [PDF]

, 2017
YesStability and safety of offshore wind turbines with mono-pile foundations, affected by nonlinear wave effect and dynamic seabed response, are the primary concerns in offshore foundation design.
Bai, Bai, Berberović, Biot, Chang, Chen, Dong-sheng Jeng, Dubravka Pokrajac, Engsig-Karup, Higuera, Higuera, Higuera, Higuera, Higuera, Hirt, Hsu, Jacobsen, Jeng, Jeng, Jeng, Jianhong, Jianhong, Jinhai Zheng, Jisheng Zhang, Kim, Kirca, Lesny, Li, Liao, Lin, Liu, Liu, Ma, Ma, Madsen, Mei, Nick Rey, Okusa, Paulsen, Paulsen, Shi, Sui, Sumer, Sumer, Sumer, Sumer, Sumer, Swan, Tang, Tian Tang, Wei, Yakun Guo, Yamamoto, Ye, Ye, Ye, Ye, Ye, Zaibin Lin, Zhang, Zhao, Zhao, Zhao, Zhao   +63 more
core   +3 more sources

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Study on the dynamic evolution of coal pore under variable pressure water injection environment

Meitan xuebao
The effects of different water injection pressures and confining pressures on the initial pore structure of coal during the water injection process in coal seams are investigated to improve the application effects of water injection technology in dust ...
Ming YANG, Longxiang HAN, Tiegang ZHANG, Jianliang GAO, Min HE, Xuebo ZHANG   +5 more
doaj   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Variation of Pore Water Pressure in Tailing Sand under Dynamic Loading

Shock and Vibration, 2018
Intense vibration affects the pore water pressure in a tailing dam, with the tendency to induce dam liquefaction. In this study, experiments were performed wherein model tailing dams were completely liquefied by sustained horizontal dynamic loading to ...
Jia-xu Jin, Hong-zhi Cui, Li Liang, Shi-wang Li, Ping-yi Zhang   +4 more
doaj   +1 more source

Accumulation of Pore Pressure in a Soft Clay Seabed around a Suction Anchor Subjected to Cyclic Loads

Journal of Marine Science and Engineering, 2019
A suction anchor is an appealing anchoring solution for floating production. However, the possible effects of residual pore pressure can be rarely found any report so far in term of the research and design.
Hui Li, Xuguang Chen, Cun Hu, Shuqing Wang, Jinzhong Liu   +4 more
doaj   +1 more source

Response of Step-Like Landslide to Pore-Water Pressure under the Action of Typhoon and Rainstorm

Geofluids, 2022
Step-like landslides have been attracting more and more attentions because of their displacement with step-like characteristics. At present, there are few studies about the mechanism of a step-like landslide from the perspective of its response to pore ...
Zhijie Huang, Wenbin Jian, Qingling Liu, Hongqiang Dou   +3 more
doaj   +1 more source

Capillary rise dynamics of liquid hydrocarbons in mesoporous silica as explored by gravimetry, optical and neutron imaging: Nano-rheology and determination of pore size distributions from the shape of imbibition fronts

, 2015
We present gravimetrical, optical, and neutron imaging measurements of the capillarity-driven infiltration of mesoporous silica glass by hydrocarbons. Square-root-of-time Lucas-Washburn invasion kinetics are found for linear alkanes from n-decane (C10 ...
Egelhaaf, Stefan U., Gruener, Simon, Hermes, Helen E., Huber, Patrick, Schillinger, Burkhard   +4 more
core   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Two-phase, passive separator-and-filter assembly [PDF]

, 1974
Assembly separates liquid from gas by passive hydrophilic/hydrophobic material approach. Apparatus is comprised of porous glass hydrophilic tubes. Quantity, lateral size, and pore size of glass tubes are determined by particular design requirements with ...
Erickson, A. C., Porter, F. J., Jr.
core   +1 more source