Results 71 to 80 of about 422,597 (347)

Wave-Induced Pore-Pressure Response on a Submarine Pipeline Buried in Seabed Sediments - Experiment and Numerical Verification - [PDF]

, 1998
The response on sandy seabed sediments to a harmonically oscillating water-table, with a special consideration of the wave-induced pore-pressure oscillations around a pipeline buried in seabed sediments, is studied in the present work experimentally and ...
Maeno, Shiro, Magda, Waldemar, Nago, Hiroshi   +2 more
core   +1 more source

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

Molecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li, Shuichi Tatarano, Hirofumi Yoshino, Saeki Saito, Mitsuhiko Tominaga, Junya Arima, Ikumi Fukuda, Takashi Sakaguchi, Ryosuke Matsushita, Yasutoshi Yamada, Hideki Enokida   +10 more
wiley   +1 more source

Controlling Effects of Residual Deformation on Pore Pressure: A Loess Soil Case

Shock and Vibration, 2019
What the role of each phase medium plays and how their interactions do work should be essential problems to understand dynamic behaviours of soils. In order to disclose interactions between solid, water, and air phases of soils, we applied loess samples ...
Kun Liu, Lanmin Wang, Wentong Tian, Zhenming Wang, Na Li, Yu Sun, Junjie Sun   +6 more
doaj   +1 more source

Landslides in sensitive soils, Tauranga, New Zealand. [PDF]

, 2013
In the Tauranga region sensitive soil failures commonly occur after heavy rainfall events, causing considerable infrastructure damage. Several notable landslides include a large failure at Bramley Drive, Omokoroa in 1979, the Ruahihi Canal collapse in ...
Cunningham, Michael J., Jorat, M.E., Lowe, David J., Moon, Vicki G., Morz, T., Wyatt, Justin Burns   +5 more
core   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Research on landslide displacement prediction method considering pore water pressure

Zhongguo dizhi zaihai yu fangzhi xuebao
Landslide displacement prediction is a critical component of disaster prevention and mitigation. Rainfall infiltration directly affects the distribution of pore water pressure within the landslide mass, and the dynamic variation of pore water pressure ...
Yu QIAN, Li WANG, Bao SHU, Hao XU, Bin CHEN, Tianyu GENG, Hanwen WU   +6 more
doaj   +1 more source

Optimization of a pressurization methodology for extracting pore-water [PDF]

Chemosphere, 2005
Sediment toxicity can be assessed by conducting pore-water toxicity assays with standard water column organisms. Several methods have been developed for sampling pore-water. Centrifugation and pressurization methods are recommended when large volumes of pore-water are required to perform toxicity assays.
Lopes, Isabel, Ribeiro, Rui
openaire   +3 more sources

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Study of the Pore Water Pressure Development Characteristics of PHC Pipe Piles in Soft Soil Foundations

Buildings
When constructing hollow prestressed high-strength concrete (PHC) pipe piles in soft soil foundations, the generation and dissipation of pore water pressure can induce negative friction on the pile.
Zhaolin Jia, Han Wu, Shuaiqi He, Qixiang Zhao, Xiaoxu Zhang   +4 more
doaj   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source