Results 11 to 20 of about 5,958 (212)

The Effect of Poria cocos Polysaccharide PCP-1C on M1 Macrophage Polarization via the Notch Signaling Pathway [PDF]

open access: yesMolecules, 2023
The homogeneous galactoglucan PCP-1C extracted from Poria cocos sclerotium has multiple biological activities. The present study demonstrated the effect of PCP-1C on the polarization of RAW 264.7 macrophages and the underlying molecular mechanism ...
Xuerui Hu   +7 more
doaj   +2 more sources

Poria Acid, Triterpenoids Extracted from Poria cocos, Inhibits the Invasion and Metastasis of Gastric Cancer Cells

open access: yesMolecules, 2022
Background: Poria cocos (P. cocos) is an important medicinal fungus in traditional Chinese medicine. Poria acid (PA), a triterpenoid compound, is an effective component of traditional Chinese medicine P. cocos.
Haibo Wang   +7 more
doaj   +3 more sources

Changes in the Volatile Flavor Substances, the Non-Volatile Components, and the Antioxidant Activity of Poria cocos during Different Drying Processes [PDF]

open access: yesMolecules
Poria cocos (Schw.) wolf (P. cocos) is an important medicinal material with both therapeutic and edible properties. This study investigated volatile constituents, amino acids, proteins, polysaccharides, triterpenoid ingredients, and alcohol-soluble ...
Chuqian Gao   +6 more
doaj   +2 more sources

Bioinformatics Analysis, Expression Profiling, and Functional Characterization of Heat Shock Proteins in Wolfi-poria cocos [PDF]

open access: yesBioengineering, 2023
Heat shock proteins (HSPs) play critical roles in regulating different mechanisms under high-temperature conditions. HSPs have been identified and well-studied in different plants.
Xin Hu   +9 more
doaj   +2 more sources

From Genes to Healing: The Protective Mechanisms of Poria cocos Polysaccharide in Endometrial Health [PDF]

open access: yesCurrent Issues in Molecular Biology
The aim of this study is to investigate the therapeutic effect of Poria cocos polysaccharide (PCP) on bovine endometritis. Initially, an inflammation model was induced using LPS-treated bovine endometrial epithelial cells (BEND) to identify the ...
Yongxi Huang   +10 more
doaj   +2 more sources

Identification of squalene epoxidase in triterpenes biosynthesis in Poria cocos by molecular docking and CRISPR-Cas9 gene editing [PDF]

open access: yesMicrobial Cell Factories
Background Squalene epoxidase is one of the rate-limiting enzymes in the biosynthetic pathway of membrane sterols and triterpenoids. The enzyme catalyzes the formation of oxidized squalene, which is a common precursor of sterols and triterpenoids. Result
Xiao-liu Liu   +6 more
doaj   +2 more sources

Advances in Understanding the Structure and Biological Activity of Poria cocos Polysaccharides [PDF]

open access: yesShipin Kexue, 2023
Poria cocos, an important edible and medicinal material, has obvious diuretic, spleen-enhancing and tranquilizing functions. Polysaccharides are one of the most important bioactive ingredients in P. cocos. Polysaccharides from P.
LIU Peiyao, WANG Kun, LIANG Shan, LI Pan, DU Bing
doaj   +1 more source

The Effect of Polysaccharide of Poria cocos on Key Metabolites of Bifidobacterium BB-12

open access: yesShipin gongye ke-ji, 2022
In order to explore the key metabolites of Bifidobacterium animalis spp. lactis BB-12 metabolizing polysaccharides of Poria cocos, a non-targeted metabolomics method based on liquid chromatography-mass spectrometry (LC-MS/MS) was used, and glucose was ...
Tianyang ZHANG   +3 more
doaj   +1 more source

Efficacy and Pharmacological Mechanism of Poria cocos-Based Formulas Combined With Chemotherapy for Ovarian Cancer: A Integrated Systems Pharmacology Study

open access: yesFrontiers in Pharmacology, 2022
Previous studies have shown that Poria cocos-based formulas combined with chemotherapy can improve the quality of life of ovarian cancer patients. However, the results are still controversial.
Xinya Peng   +6 more
doaj   +1 more source

Untargeted metabolomics analysis reveals dynamic changes in co-fermentation with human milk-derived probiotics and Poria cocos

open access: yesFrontiers in Microbiology, 2022
IntroductionTo develop functional foods with traditional medicines and homologous food ingredients as well as human milk-derived probiotics, the co-fermentation process of two probiotics, Lactobacillus plantarum R9 and Lactobacillus gasseri B1-27 ...
Qishan Wang   +11 more
doaj   +1 more source

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