Carboxymethylated <i>Poria cocos</i> Polysaccharides Mitigate Cisplatin-Induced Hepatorenal Injury by Activating the PLC-PKC-Nrf2 Signaling Pathway. [PDF]
CMP protects against cisplatin‐induced hepatorenal damage by suppressing inflammation and oxidative stress. CMP reduces serum ALT, AST, BUN, and Cr levels, ameliorates tissue pathological injury, inhibits pro‐inflammatory cytokine production and immune cell infiltration, and restores cellular antioxidant capacity.
He L +8 more
europepmc +2 more sources
ObjectiveTo improve the utilization of Poria cocos resources.MethodsThis paper employs cellulase and xylanase in combination with Monascus for the solid-state fermentation of Poria cocos, and measures the changes in the content of alkali-soluble ...
PENG Cancan +3 more
doaj +2 more sources
Poria cocos: traditional uses, triterpenoid components and their renoprotective pharmacology [PDF]
Poria cocos and its surface layer of Poria cocos (Schw.) Wolf (Polyporaceae), are used in traditional Chinese medicine for its diuretic and renoprotective effects. Phytochemical studies have shown that lanostane and 3,4-seco-lanostane tetracyclic triterpenoids are the main components of P. cocos and its surface layer.
Ying-Yong Zhao
exaly +5 more sources
Cytotoxic Lanostanoids from Poria cocos
Six new and 16 known lanostanoids were isolated from the sclerotia of Poria cocos. The structures of the new isolates were elucidated to be 16α-hydroxy-3-oxo-24-methyllanosta-5,7,9(11),24(31)-tetraen-21-oic acid (1), 3β,16α,29-trihydroxy-24-methyllanosta-
Yu-Ming Hsu +21 more
core +4 more sources
DNA sequencing analysis of ITS and 28S rRNA of Poria cocos [PDF]
We determined the DNA sequences of the internal transcribed spacer 1 and 2 (ITS 1 and 2), the 5.8S rRNA gene and most of the 28S rRNA gene of Poria cocos for the first time, and conducted analysis of 20 samples including cultured mycelias and crude drug ...
Kakiuchi, Nobuko +2 more
core +5 more sources
The Lanostane Triterpenoids in Poria cocos Play Beneficial Roles in Immunoregulatory Activity
Poria cocos (Schwein) F.A. Wolf (syn. Wolfiporia cocos) dried sclerotium, called fuling, is an edible, saprophytic fungus commonly used as a tonic and anti-aging traditional Chinese medicine. It is traditionally used in combination with other traditional
Chien-Liang Chao +4 more
doaj +2 more sources
Poria cocos Solid-State Fermentation for Bioprocessing Tartary Buckwheat: Nutritional Enhancement, Antioxidant Activity, and Application in Steamed Bread [PDF]
This study pioneered the application of Poria cocos solid-state fermentation (SSF) to Tartary buckwheat (TB). We aimed to enhance its nutritional value, antioxidant activity, and bioaccessibility through fungal biotransformation.
Wendi Fan +6 more
doaj +2 more sources
The isolation, identification and determination of dehydrotumulosic acid in Poria cocos. [PDF]
Poria cocos (Fuling), a popular Chinese medicinal (CM) herb of fungal origin, has been included in many combinations with other CM herbs for its traditionally claimed activities of inducing diuresis, excreting dampness, invigorating the spleen and ...
Bi, Kaishun +3 more
core +6 more sources
Effects of Poria cocos extract on metabolic dysfunction-associated fatty liver disease via the FXR/PPARα-SREBPs pathway [PDF]
Despite the increase in the global prevalence of metabolic dysfunction-associated fatty liver disease (MAFLD), no approved drug currently exists for the disease. Poria cocos (Schw.) Wolf (P.
Jinbiao He +12 more
doaj +2 more sources
Poria cocos Wolf extracts represses pigmentation in vitro and in vivo
In skin, melanocytes determine skin color using melanogenesis, which induces protective mechanism to oxidative stress and UV damage. However, when melanin is excessive produced by the various stimulus, the accumulated melanin induces hyperpigmentation ...
Hwa Jun Cha, HyunKyung Lee
core +4 more sources

