Results 51 to 60 of about 4,165 (171)

Study on the anticancer activity of Poria cocos extract mediated gold nanoparticles in the treatment of pancreatic cancer

Materials Research Express, 2021
Poria cocos , a fungus used extensively in the Chinese herbal medicine, has been known for myriad of pharmacological applications. There is a growing body of evidence on developing medications for antitumor therapies.
Miao Nie, Peijun Sun
doaj   +1 more source

Food and Medicinal Homologous Substances in Sleep Disorders Improvement: Current Advances and Future Perspectives

Food Frontiers, Volume 7, Issue 4, July 2026.
The schematic diagram illustrating the improvement mechanisms of six typical FMH substances and their main active ingredients in different sleep disorders. ABSTRACT Sleep integrates many brain and peripheral processes, profoundly influencing well‐being.
Wenjing Wen, Qili Li, Chenghao Lv, Jing Wen, Yihan Zhang, Yuhang Yi, Tao Li, Fang Wang, Yibo Luo, Si Qin   +9 more
wiley   +1 more source

Laparoscopic Delivery of a MnO2‐P‐ICG Patch for Photodynamic Therapy and NK Cell‐Driven Immunotherapy in Hepatocellular Carcinoma

Advanced Science, Volume 13, Issue 32, 9 June 2026.
This study proposes a flexible MnO2‐P‐ICG nanofiber patch for laparoscopic treatment of liver tumors. The patch alleviates tumor hypoxia and induces photodynamic therapy (PDT) triggered immunogenic cell death, thereby activating the cGAS‐STING pathway and, in synergy with pachymaran, promoting NK cell–mediated innate immunity. This synergistic strategy
Jie Lin, Haoqi Pan, Ke Wu, Junjie Nan, Jinyao Dai, Yushun Chang, Hao Shen, Qingxuan Ye, Haowen Lu, Yuxuan Shen, Boqiang Liu, Ming Wu, Jicheng Yu, Xiujun Cai, Dong Cen   +14 more
wiley   +1 more source

Multi-target regulatory mechanism of Yang Xin Tang − a traditional Chinese medicine against dementia

Chinese Medicine, 2023
Background Yang Xin Tang (YXT) is a traditional Chinese herbal preparation which has been reported to improve cognitive function and memory in patients with dementia.
Tung Yan Lo, Anthony Siu Lung Chan, Suet Ting Cheung, Lisa Ying Yung, Manton Man Hon Leung, Yung Hou Wong   +5 more
doaj   +1 more source

Mechanisms of Gui Zhi Fu Ling Formula in Liver Fibrosis: Metabolomics and Gut Microbiota Analysis

eFood, Volume 7, Issue 3, June 2026.
Our study was based on the efficacy of the phenotype in an animal model and used multi‐omics to explore the mechanism of action of the compound. We found that Gui Zhi Fu Ling Formula may ameliorate hepatic fibrosis potentially associated with increased hepatic EPA and the expression of gut Pseudomonas.
Xiaoliang Deng, Yanqun Luo, Ying Gao, Yi Su, Haiping Xue, Tao Wu   +5 more
wiley   +1 more source

Food and Medicine Homologous Plants in Osteoporosis: A Scoping Review of Preclinical Evidence

Food Science &Nutrition, Volume 14, Issue 6, June 2026.
Food and medicine homologous (FMH) plants and their bioactive compounds exhibit potential osteoprotective effects through multiple complementary mechanisms, including estrogen‐like signaling, attenuation of oxidative stress, modulation of the gut microbiota–bone axis, and regulation of autophagy.
Long Zhao, Xiao‐li Dong, Rui‐ting Li, Qu‐huan Ma, Xiao‐feng Shi   +4 more
wiley   +1 more source

Poria cocos Polysaccharides Regulate Anxiety and Depression-like Behaviors Induced by Lipopolysaccharide through NF-κB and NLRP3 Signaling Pathways

Shipin gongye ke-ji, 2023
Objective: To explore the effect of Poria cocos polysaccharides (Poria cocos polysaccharide, PPS) on anxiety and depression-like behaviors induced by lipopolysaccharide (LPS) and analyze its mechanism. Methods: BV-2 cells were divided into control group,
Yunjing SHI, Yuxia LI
doaj   +1 more source

Protein Tyrosine Phosphatase 1B‐Mediated Granulosa Cell Insulin Resistance Links Metabolic Stress to Aging‐Relevant Ovarian Dysfunction and Is Reversed by Gengnianchun

Aging Cell, Volume 25, Issue 6, June 2026.
Metabolic stress induces insulin resistance and upregulates PTP1B in granulosa cells, leading to aging‐relevant ovarian dysfunction. Gengnianchun (GNC) suppresses PTP1B, restores IRS1–AKT2–GLUT4 signaling, and preserves follicles, highlighting PTP1B as a therapeutic target for ovarian dysfunction in metabolically vulnerable states.
Yanqiu Rao, Ting Xu, Yan Ding, Jun Li, Lingyun Gao, Yun Wang, Wenjun Wang   +6 more
wiley   +1 more source

Biochar‐Based Materials for Electrochemical Energy Storage

ChemElectroChem, Volume 13, Issue 9, 5 May 2026.
Overview of biochar application in electrochemical energy storage. The global transition toward sustainable energy technologies is reshaping the design principles of electrochemical energy storage systems. Biochar, a tunable, carbon‐rich material derived from biomass, has emerged as a promising platform for next‐generation electrodes due to its ...
Valerio C. A. Ficca, Afef Dhaffouli, Rocco Cancelliere   +2 more
wiley   +1 more source

Altered Effective Connectivity of Precuneus Subregions and Associated Gene Profiles in Chronic Insomnia Disorder Patients Before and After Treatment

Brain and Behavior, Volume 16, Issue 5, May 2026.
Granger causality analysis seeded on the precuneus subregions was employed to detect effective connectivity alterations at pre‐ and post‐treatment. The treatment included 6 weeks of modified suanzaoren decoction (a TCM widely used to improve insomnia) or estazolam. Finally, correlation analyses and a neuroimaging–transcription association analysis were
Zhiguo Guo, Leyi Zhang, Yiding Han, Haohao Yan, Ping Yao, Dongsheng Lv, Yonggui Yuan, Jingping Zhao, Lixia Chen, Wenbin Guo   +9 more
wiley   +1 more source