Results 61 to 70 of about 4,165 (171)

Poria cocos Wolf extracts represses pigmentation in vitro and in vivo

Cellular and Molecular Biology, 2018
In skin, melanocytes determine skin color using melanogenesis, which induces protective mechanism to oxidative stress and UV damage. However, when melanin is excessive produced by the various stimulus, the accumulated melanin induces hyperpigmentation disease such as melasma, freckles, Melanism ware induced.
HyunKyung, Lee, Hwa Jun, Cha
openaire   +3 more sources

Fungal Polysaccharides as Next‐Generation Bioactive: Advances in Structure–Activity Mapping, Mode of Action, and Biotechnological Horizons

Food Frontiers, Volume 7, Issue 3, May 2026.
ABSTRACT Fungal polysaccharides (FPs) represent a diverse class of bioactive macromolecules widely studied for their nutritional, therapeutic, and biotechnological value. This review synthesizes recent advances (2020–2025) in the structural characterization, biological functions, and translational potential of FPs.
Muhammad Aaqil, Feng Zhang, Jingchuan Zheng, Muhammad Kamil, Yuwei Guo, Cunchao Zhao, Yang Tian   +6 more
wiley   +1 more source

A new antitumor polysaccharide from the mycelia of Poria cocos Wolf.

Chemical and Pharmaceutical Bulletin, 1983
A new antitumor polysaccharide, H11, was isolated from the mycelia of Poria cocos Wolf. The structure of H11 is a (1, 3)-(1, 6)-β-D-glucan having a molecular weight of 5×106.
Kanayama, Hisanori, Adachi, Norihiko, Togami, Masatoshi   +2 more
openaire   +3 more sources

Pachymic Acid Alleviates Non‐Alcoholic Fatty Liver Disease via FGF21‐Mediated Inhibition of the p38 MAPK Pathway

Food Science &Nutrition, Volume 14, Issue 5, May 2026.
Pachymic acid alleviates non‐alcoholic fatty liver disease via FGF21‐mediated inhibition of the p38 MAPK pathway. Pachymic acid (PAC) exerts anti‐ non‐alcoholic fatty liver disease (NAFLD) effects by promoting FGF21 expression, activating FGF21/FGFR1 signaling, and thereby suppressing p38 MAPK phosphorylation. ABSTRACT Non‐alcoholic fatty liver disease
Lijuan Nie, Dehong Ma, Xinke Deng, Aga Erbu, Fanli Wang, Wenshuo Shi, Zixuan Li, Huantian Cui, Weibo Wen   +8 more
wiley   +1 more source

Anshen Jieyu Decoction: A Promising Remedy for Depression via AKT/mTOR Pathway Modulation in CUMS Rats

Brain and Behavior, Volume 16, Issue 4, April 2026.
An Shen Jie Yu Tang ameliorates depression‐like behaviors in chronically stressed rats. Its mechanism involves suppressing HPA axis hyperactivity and activating the hippocampal AKT/mTOR signaling pathway, leading to neuroprotective effects. ABSTRACT Objective To investigate the effects of An Shen Jie Yu Tang (ASJYD) on hippocampal morphology, AKT/mTOR ...
Zhen Li, Zijun Ji, Zehao Zhang, Xuzhang Wang, Hongyue Yu, Dongrun Yang, Huijin Zhang, Yongsheng Liu, Zhuxin Sui   +8 more
wiley   +1 more source

DNA Sequencing Analysis of ITS and 28S rRNA of Poria cocos

Biological and Pharmaceutical Bulletin, 2007
We determined the DNA sequences of the internal transcribed spacer 1 and 2 (ITS 1 and 2), the 5.8S rRNA gene and most of the 28S rRNA gene of Poria cocos for the first time, and conducted analysis of 20 samples including cultured mycelias and crude drug materials obtained from various localities and markets. Direct sequencing of the ITS 1 and 2 regions
Atsumi, Toshiyuki, Kakiuchi, Nobuko, Mikage, Masayuki   +2 more
openaire   +3 more sources

Zhenyuan Solid Drink Ameliorates Inflammation and Oxidative Stress in Isoproterenol‐Induced Ischemic Myocardial Infarction via TLR4/NF‐κB Pathway and PI3K/AKT1/NRF2 Pathway in Rats

Food Science &Nutrition, Volume 14, Issue 4, April 2026.
ZYSD exerts curative and preventive cardioprotection against isoproterenol‐induced myocardial infarction through synergistic interaction with probiotics, exerting antioxidant and anti‐inflammatory effects. ABSTRACT Zhenyuan Solid Drink (ZYSD) is a formulation consisting of 6 medicinal herbs that can be used as both food and medicinal materials in China.
Jiawen Huang, Tian Yu, Guoyi Li, Kechao Nie, Donghua Liu, Cong Meng, Xiaoling Shen, Linchun Fu, Liang Long, Zhuotao Fu, Zhitong Deng, Yingjie Hu   +11 more
wiley   +1 more source

Macrophage-mimicking nanotherapy for attenuation of acute pancreatitis

Materials Today Bio
Acute pancreatitis (AP) is a highly fatal pancreatic inflammation. In recent years, synthetic nanoparticles have been extensively developed as drug carriers to address the challenges of systemic adverse reactions and lack of specificity in drug delivery.
Fengyu Shi, Akmal Ergashev, Zhenyan Pan, Hongwei Sun, Lingming Kong, Yuepeng Jin, Tan Zhang, Zhu Liu, Haonan Xie, Jinhui Wang, Huiping Li, Yi Wang, Lifei Zheng, Jianliang Shen, Andreas Herrmann, Gang Chen, Hongru Kong   +16 more
doaj   +1 more source

Poria cocos as a Functional Food for Diabetes and Diabetes‐Related Foot Ulcers

AgriFood: Journal of Agricultural Products for Food, Volume 2, Issue 1, Page 30-38, March 2026.
Poria cocos is known as an edible mushroom for food and medicine. Poria cocos and its terpenes and terpenoids serve as novel remedies to treat diabetes and its ulcers. Its mode of actions includes reduction of insulin resistance, starch digestion and inflammation as well as promotion of blood vessel formation. ABSTRACT Poria cocos is a medicinal fungus
Yi‐San Lee, Tien‐Fen Kuo, Greta Yang, Wen‐Chin Yang   +3 more
wiley   +1 more source

ShenQi DiHuang Decoction (SQDHD) Ameliorates Neuroinflammation and Neuropsychiatric Manifestations in Pristane Induced Lupus Mice via Blocking JAK1‐STAT3 Pathway

CNS Neuroscience &Therapeutics, Volume 32, Issue 3, March 2026.
SQDHD exerts neuroprotective effects and alleviates behavioral deficits in PIL mice, likely by inhibiting the JAK1‐STAT3 pathway in activated CVECs. These findings underscore the therapeutic potential of SQDHD and establish it as a promising candidate for the treatment of NPSLE.
Jie Chen, Chumiao Cui, Fei Xu, Jiayan Feng, Jingyu Chen, Xueru Wang, Hui Yuan, Chenye Jin, Yutian Li, Yang Yun   +9 more
wiley   +1 more source