Results 41 to 50 of about 78,386 (279)
Porphyromonas gingivalis periodontal infection and its putative links with Alzheimer’s disease [PDF]
, 2015 Periodontal disease (PD) and Alzheimer’s disease (AD) are inflammatory conditions affecting the global adult population. In the pathogenesis of PD, subgingival complex bacterial biofilm induces inflammation that leads to connective tissue degradation and
Crean, Stjohn +4 more
core +7 more sources
PLoS ONE, 2013 Porphyromonas gingivalis is considered as a major etiological agent in periodontal diseases and implied to result in gingival inflammation under orthodontic appliance. rag locus is a pathogenicity island found in Porphyromonas gingivalis.
Yi Liu +4 more
doaj +1 more source
Gingipain aminopeptidase activities in Porphyromonas gingivalis [PDF]
bchm, 2012 Abstract Bestatin, a specific inhibitor of metalloaminopeptidases, inhibits the growth of Porphyromonas gingivalis. To identify its target enzyme, a library of fluorescent substrates was used but no metalloaminopeptidase activity was found. The aminopeptidase activity of P.
Florian Veillard +4 more
openaire +4 more sources
Interaction Between Autophagy and Porphyromonas gingivalis-Induced Inflammation
Frontiers in Cellular and Infection Microbiology, 2022 Autophagy is an immune homeostasis process induced by multiple intracellular and extracellular signals. Inflammation is a protective response to harmful stimuli such as pathogen microbial infection and body tissue damage.
Sen Kang +3 more
doaj +1 more source
Porphyromonas gingivalis Strain Diversity [PDF]
Journal of Clinical Microbiology, 2009 ABSTRACT Porphyromonas gingivalis is implicated in the etiology of chronic periodontitis. Genotyping studies suggest that genetic variability exists among P. gingivalis strains; however, the extent of variability remains unclear and regions of variability remain largely unidentified. To assess
Christina O. Igboin +2 more
openaire +3 more sources
Circulation Research, 2020 Supplemental Digital Content is available in the text. Rationale: Atherosclerotic cardiovascular diseases are the leading cause of mortality worldwide. Atherosclerotic cardiovascular diseases are considered as chronic inflammation processes.
Mengru Xie +10 more
semanticscholar +1 more source
Lipoprotein modifications by gingipains of Porphyromonas gingivalis [PDF]
Journal of Periodontal Research, 2018 AbstractBackground and ObjectiveSeveral studies have shown an association between periodontitis and cardiovascular disease (CVD). Atherosclerosis is the major cause of CVD, and a key event in the development of atherosclerosis is accumulation of lipoproteins within the arterial wall.
J. Lönn +5 more
openaire +6 more sources
PLoS ONE, 2016 Aim"Perioceutics" including antimicrobial therapy and host modulatory therapy has emerged as a vital adjunctive treatment of periodontal disease. Melatonin level was significantly reduced in patients with periodontal diseases suggesting melatonin could ...
Wei Zhou +5 more
doaj +1 more source
Porphyromonas gingivalis lipopolysaccharide alters atherosclerotic-related gene expression in oxidized low-density-lipoprotein-induced macrophages and foam cells [PDF]
, 2011 The molecular mechanism between atherosclerosis formation and periodontal pathogens is not clear although positive correlation between periodontal infections and cardiovascular diseases has been reported.
de Winther +23 more
core +2 more sources
Placental Trophoblast Responses to Porphyromonas gingivalis Mediated by Toll-like Receptor-2 and -4
Journal of Dentistry Indonesia, 2013 Trophoblast participates in preventing allorecognition and controlling pathogens that compromise fetal wellbeing. Toll-like receptors recognize conserved sequences on the pathogens surface and trigger effector cell functions.
Banun Kusumawardani +3 more
doaj +1 more source