Results 61 to 70 of about 43,687 (287)

Hemin availability induces coordinated DNA methylation and gene expression changes in Porphyromonas gingivalis

mSystems, 2023
Periodontal disease is a chronic inflammatory disease in which the oral pathogen Porphyromonas gingivalis plays an important role. Porphyromonas gingivalis expresses virulence determinants in response to higher hemin concentrations, but the underlying ...
Ricardo Costeira, Joseph Aduse-Opoku, Jon J. Vernon, Francisco Rodriguez-Algarra, Susan Joseph, Deirdre A. Devine, Philip D. Marsh, Vardhman Rakyan, Michael A. Curtis, Jordana T. Bell   +9 more
doaj   +1 more source

Programmable Paracrine‐Mimetic Microneedle System for Temporal Regulation of Cardiac Repair

Advanced Science, EarlyView.
Temporal signaling is encoded into a programmable paracrine‐mimetic microneedle patch via tris(2,2'‐bipyridyl)dichlororuthenium(II) hexahydrate/sodium persulfate‐tuned hydrogel microparticles that deliver TGF‐β, IGF‐1, and VEGF over phase‐matched 7‐, 14‐, and 28‐day windows.
Yichen Dai, Pengchong Du, Zhaoyang Wang, Surilige, Rangga Fokta, Renjian Tan, Xiqing Zhao, Shuoyi Zhang, Yuecheng Wang, Yixin Zhang, Ziliang Fu, Rui Gong, Cheng Jiang, Yisheng He, Qiguang Wang, Renke Li, Khoon Lim, Junnan Tang, Xiaolin Cui   +18 more
wiley   +1 more source

Porphyromonas gingivalis ligada a enfermedad periodontal y su relación con la artritis reumatoide: identificación de nuevos mecanismos biomoleculares

Acta Odontológica Colombiana, 2020
Objetivo: revisar la literatura científica existente con respecto a la patogenicidad de Porphyromonas gingivalis, ligada a enfermedad periodontal (EP) (disbiosis oral), y su asociación con la activación de mecanismos fisiopatológicos en la artritis ...
Oscar Vicente Vergara Serpa, Alonso Cortina Gutiérrez, Diego Antonio Serna Otero, José Fernando Zuluaga Salazar, Carlos Andres Reyes Jaraba   +4 more
doaj   +1 more source

The polymicrobial pathogenicity of Porphyromonas gingivalis

Frontiers in Oral Health
Accumulating microbiome data and mechanistic studies in vitro and in vivo have refined our understanding of the oral microbiota as a functionally integrated polymicrobial community. Emergent properties of these communities are driven to a large extent by interspecies communication which can be based on physical association, secreted small molecules or ...
Richard J. Lamont, Masae Kuboniwa
openaire   +3 more sources

Targeting the YAP‐BST2 Axis Overcomes Intrinsic Anti‐PD‐1 Resistance in Metastatic Gastric Cancer

Advanced Science, EarlyView.
Concurrent YAP hyperactivation and Tp53 loss in Atp4b‐expressed parietal cell lineage drives gastric cancer initiation, multi‐organ metastasis, and intrinsic resistance to anti‐PD‐1 therapy. BST2 emerges as a direct YAP‐TEAD transcriptional target that engages PIRA2 on myeloid cells to establish an immunosuppressive microenvironment.
Weihong Zhang, Shilong Wang, Meng Wang, Ruixian Yu, Jingwu Yue, Lin Shao, Hui Zhang, Mengwen Zhu, Luyang Tian, Shuting Cheng, Weimin Qin, Yang Tang, Yi Han, Wenjia Wang, Liwei An, Yan Meng, Shi Jiao, Zhaocai Zhou   +17 more
wiley   +1 more source

Effect Virgin Coconut Oil On Porphyromonas Gingivitis, Staphylococcus Aureus Bacteria

International Dental Journal
Aim or purpose: Study aims to determine the efficacy of Virgin Coconut Oil in inhibiting bacterial growth. Porphyromonas gingivalis and Staphylococcus aureus as bacterial agents of periodontal disease Materials and methods: This research employs an ...
Hasanuddin Thahir, Nurul Azizah, Andi Keisha Faradiza Nawir   +2 more
doaj   +1 more source

Antibacterial test of Peperomia pellucida (L.) Kunth extract against Porphyromonas Gingivalis as a potential herb for periodontitis: a laboratory experiment

Padjadjaran Journal of Dentistry, 2023
Introduction: Periodontitis is a multifactorial inflammatory disease which is generally caused by plaque accumulation. Many studies have shown that Porphyromonas gingivalis (Pg) is the main etiological agent that contributes to chronic periodontitis ...
Dewi Lidya Ichwana Nasution, Sri Tjahajawati, Ratna Indriyanti, Amaliya Amaliya, Rina Putri Noer Fadilah, Rahman Mutiara   +5 more
doaj   +1 more source

Porphyromonas gingivalis, ethanol, and chronic diseases. [PDF]

, 2022
This dissertation is an investigation into the relationships among Porphyromonas gingivalis, ethanol, and a series of chronic diseases, focusing primarily on atherosclerosis.
Short, Nicholas Alan
core   +1 more source

Rewriting Tumor Immunity With Bacterial Membrane Vesicles: A Versatile and Potent Therapeutic Strategy

Advanced NanoBiomed Research, EarlyView.
Bacterial membrane vesicles (BMVs) emerge as promising platforms for cancer immunotherapy owing to their intrinsic adjuvant properties and tunable cargo delivery capabilities. Their ability to modulate the tumor microenvironment, enhance antitumor immune responses, and support personalized therapeutic strategies highlights their growing potential as ...
Md Sifat Rahi, Md Mijanur Rahman, Asma Talukder, Urooj Yousaf Virk, Jennifer C. Wilson, Nigel McMillan, Ming Q. Wei   +6 more
wiley   +1 more source

Porphyromonas gingivalis in Dental Caries: Prevalence and Association with Diabetes and Smoking

Journal of Medical Sciences and Health
Background and objectives: Porphyromonas gingivalis is an intraoral anaerobic bacterium that causes periodontal disease. Diabetes and smoking are thought to be the main associated risk factors. The aim of this study was to assess the prevalence of P.
Tarana Sarwat, Lipika Gaur, Zarine Khan, Pranjalika Phukan, Dalip K Kakru   +4 more
doaj   +1 more source