Results 61 to 70 of about 56,408 (287)

Interaction between extracellular matrix molecules and microbial pathogens: evidence for the missing link in autoimmunity with rheumatoid arthritis as a disease model. [PDF]

, 2014
Rheumatoid arthritis (RA) is an autoimmune disease characterized by inflammation followed by tissue rebuilding or fibrosis. A failure by the body to regulate inflammation effectively is one of the hallmarks of RA.
Bella, Blombäck, Chang, De Almeida, De Rycke, Everse, Fan, Gregersen, Hynes, Ioan-Facsinay, Klareskog, Li, Mahdi, McInnes, Meyer, Mikuls, Mundlos, Panayi, Perry, Ruiz-Esquide, Scher, Scott, Sofat, Symmons, Van Beers, van der Woude, van Heemst, Vincent, Wegner, Wellcome Trust Case Control Consortium, Weyand, Williams   +31 more
core   +6 more sources

Research progress on the structure and function of the type IX secretion system of Porphyromonas gingivalis

口腔疾病防治, 2023
The Porphyromonas gingivalis type IX secretion system (T9SS) is a recently discovered protein secretion system that is widely distributed in Bacillus cereus. The T9SS is structurally complex and powerful.
ZHANG Ruotong, YE Wei
doaj   +1 more source

The oral microbiome and adverse pregnancy outcomes. [PDF]

, 2017
Significant evidence supports an association between periodontal pathogenic bacteria and preterm birth and preeclampsia. The virulence properties assigned to specific oral pathogenic bacteria, for example, Fusobacterium nucleatum, Porphyromonas ...
Angolkar, Mubashir, Babbar, Shilpa, Cobb, Charles M., Derman, Richard J., Kelly, Patricia J., Williams, Karen B.   +5 more
core   +3 more sources

Photoinactivation and Photoablation of Porphyromonas gingivalis

Pathogens, 2023
Several types of phototherapy target human pathogens and Porphyromonas gingivitis (Pg) in particular. The various approaches can be organized into five different treatment modes sorted by different power densities, interaction times, effective wavelengths and mechanisms of action.
David M. Harris, John G. Sulewski
openaire   +3 more sources

Roles of Porphyromonas gingivalis and its virulence factors in periodontitis.

Advances in Protein Chemistry and Structural Biology, 2020
Periodontitis is an infection-driven inflammatory disease, which is characterized by gingival inflammation and bone loss. Periodontitis is associated with various systemic diseases, including cardiovascular, respiratory, musculoskeletal, and reproductive
Weizhe Xu, W. Zhou, Huizhi Wang, S. Liang   +3 more
semanticscholar   +1 more source

Mitochondrial ROS participates in Porphyromonas gingivalis-induced pyroptosis in cementoblasts

Heliyon
This study aimed to investigate correlation between mitochondrial reactive oxygen species and Porphyromonas gingivalis in the process of cementoblast pyroptosis.
Weiman Sun, Tianrui Yang, Chenxu Wang, Houxuan Li, Lang Lei   +4 more
doaj   +1 more source

Hemin availability induces coordinated DNA methylation and gene expression changes in Porphyromonas gingivalis

mSystems, 2023
Periodontal disease is a chronic inflammatory disease in which the oral pathogen Porphyromonas gingivalis plays an important role. Porphyromonas gingivalis expresses virulence determinants in response to higher hemin concentrations, but the underlying ...
Ricardo Costeira, Joseph Aduse-Opoku, Jon J. Vernon, Francisco Rodriguez-Algarra, Susan Joseph, Deirdre A. Devine, Philip D. Marsh, Vardhman Rakyan, Michael A. Curtis, Jordana T. Bell   +9 more
doaj   +1 more source

Gingipain aminopeptidase activities in Porphyromonas gingivalis [PDF]

bchm, 2012
Abstract Bestatin, a specific inhibitor of metalloaminopeptidases, inhibits the growth of Porphyromonas gingivalis. To identify its target enzyme, a library of fluorescent substrates was used but no metalloaminopeptidase activity was found. The aminopeptidase activity of P.
Florian Veillard, Barbara Potempa, Marcin Poreba, Marcin Drag, Jan Potempa   +4 more
openaire   +3 more sources

Porphyromonas Gingivalis Sialidase Reshapes Gut Microbiota And Systemic Immunity

International Dental Journal
Aim or purpose: Porphyromonas gingivalis can alter the gut microbiota and serum metabolites. However, its sialidase in modulating gut microbiota composition, host metabolism, and immune responses remains unexplored.
Wu Qibing, Liu Haijie, Niu Yixi, Li Hongxia   +3 more
doaj   +1 more source

Roles of Oral Bacteria in Cardiovascular Diseases — From Molecular Mechanisms to Clinical Cases: Involvement of Porphyromonas gingivalis in the Development of Human Aortic Aneurysm

Journal of Pharmacological Sciences, 2010
Accumulating evidence suggests the involvement of Porphyromonas gingivalis (P. gingivalis), a periodontal pathogen, in cardiovascular diseases. Clinical specimens of aneurysmal tissue and dental plaque collected from patients infected with or without P ...
Koichiro Wada, Yoshinori Kamisaki
doaj   +1 more source