Results 31 to 40 of about 13,819 (183)
Background Posaconazole is effective as primary antifungal prophylaxis of invasive fungal diseases in patients with acute myeloid leukemia.Design and Methods The impact of primary antifungal prophylaxis administered during front-line chemotherapy for ...
Corrado Girmenia+14 more
doaj +1 more source
Posaconazole is a commonly used medication for antifungal prophylaxis in patients with high-risk acute leukemia, such as acute myeloid leukemia. Despite clinical data that show that posaconazole is superior to other antifungal prophylaxis medications ...
Mayur D. Mody MD+3 more
doaj +1 more source
Objective: a comparative clinical and economic analysis of posaconazole (Noxafil) for invasive mycoses (IM) prevention in patients with severe neutropenia during treatment of acute myeloid leukemia or myelodysplastic syndrome in Russia.
I. S. Krysanov+3 more
doaj +1 more source
The tablet formulation of posaconazole: clinical pharmacology and the use in patients with hematologic malignancies [PDF]
Posaconazole is a broad-spectrum triazole antifungal agent with potent activity against various fungi, including yeast and molds, including Mucorales, what makes a key difference with itraconazole and voriconazole.
Veselov A.V.
doaj +1 more source
Purpose: To assess and compare the efficacy and safety of posaconazole with fluconazole for the prevention of invasive fungal infections in children who were undergoing induction therapy for acute lymphoblastic leukemia (ALL).
Tian Zhang+6 more
doaj
Posaconazole-Induced Adrenal Insufficiency in a Case of Chronic Myelomonocytic Leukemia
Introduction. Posaconazole is an azole used in treatment and prophylaxis of a broad spectrum of fungal infections. Antifungals such as ketoconazole have been shown to cause primary adrenal insufficiency (AI) as a result of direct inhibition on the ...
Ann Miller+3 more
doaj +1 more source
Mineralocorticoid hypertension and hypokalaemia induced by posaconazole
We describe severe hypokalaemia and hypertension due to a mineralocorticoid effect in a patient with myelodysplastic syndrome taking posaconazole as antifungal prophylaxis.
Charlotte Boughton+4 more
doaj +1 more source
Posaconazole: A Review of Drug Interactions with HIV Antiretroviral Agents
The purpose of this review is to examine the literature for reports of clinically significant interactions noted amongst HIV antiretroviral medications when coadministered with posaconazole.
Mara Poulakos, Amy Henneman, Simon Leung
doaj +1 more source
Objectives: Posaconazole is a broad-spectrum triazole antifungal, with activity against various clinically important fungi. The delayed release (DR) tablet of posaconazole has been shown to have a superior pharmacokinetic profile in comparison with the ...
Parikshit S. Prayag+8 more
doaj
Background Pediatric patients undergoing hematopoietic stem cell transplantation (HSCT) are at high risk of acquiring fungal infections. Antifungal prophylaxis shortly after transplantation is therefore indicated, but data for pediatric patients under 12
Döring Michaela+8 more
doaj +1 more source