Results 31 to 40 of about 27,357 (215)

Evaluation of antifungal susceptibility and clinical characteristics in fungal keratitis in a tertiary care center in North India

open access: yesIndian Journal of Ophthalmology, 2022
Purpose: To study the antifungal susceptibility of common corneal pathogenic fungi to antifungal agents in the North Indian population. Methods: Prospective study of the antifungal sensitivity testing (natamycin, amphotericin B, voriconazole ...
Murugesan Vanathi   +5 more
doaj   +1 more source

Therapeutic drug monitoring of posaconazole delayed release tablet while managing COVID‐19–associated mucormycosis in a real‐life setting

open access: yesMycoses (Berlin), 2021
Along with COVID‐19 pandemic, India has faced an outbreak of COVID‐19–associated mucormycosis (CAM). Due to restricted availability of amphotericin B during this outbreak, clinicians were forced to use posaconazole or isavuconazole preparations as first ...
Atul K. Patel   +4 more
semanticscholar   +1 more source

Comparative pharmacoeconomic analysis of posaconazole therapy in tablet form and in suspension for invasive fungal infections prevention

open access: yesОнкогематология, 2021
The objective of the study was to conduct a comparative pharmacoeconomic analysis of the treatment with posaconazole in a tablet form for the prevention of invasive fungal infections in patients aged 13 years and older with prolonged neutropenia and ...
I. S. Krysanov   +4 more
doaj   +1 more source

Voriconazole and posaconazole therapeutic drug monitoring: a retrospective study

open access: yesAnnals of Clinical Microbiology and Antimicrobials, 2017
Background Therapeutic drug monitoring (TDM) aims to minimize the clinical impact of posaconazole and voriconazole pharmacokinetic variability. However, its benefits on clinical outcomes are still being defined.
Whitley M. Yi   +6 more
doaj   +1 more source

Repurposing of terconazole as an anti Trypanosoma cruzi agent [PDF]

open access: yes, 2019
Trypanosoma cruzi is the causative agent of Chagas disease, a parasitic infection endemic in Latin America. Currently there are no effective treatments for the chronic phase of the disease, when most patients are diagnosed, therefore the development of ...
Martínez Sayé, Melisa Soledad   +4 more
core   +1 more source

The Outcome of Antifungal Prophylaxis with Posaconazole in Patients with Acute Myeloid Leukemia: A Single-Center Study

open access: yesTurkish Journal of Hematology, 2018
Objective: Invasive fungal infections (IFIs) are a significant cause of morbidity and mortality among neutropenic patients undergoing chemotherapy for acute myeloid leukemia (AML) and stem cell transplantation.
Vildan Özkocaman   +9 more
doaj   +1 more source

Impact of glucuronide interferences on therapeutic drug monitoring of posaconazole by tandem mass spectrometry [PDF]

open access: yes, 2010
Background: Posaconazole is a novel antifungal drug for oral application intended especially for therapy of invasive mycoses. Due to variable gastrointestinal absorption, adverse side effects, and suspected drug-drug interactions, therapeutic drug ...
Burghardt, Stephan   +4 more
core   +1 more source

Establishment and Verification of UPLC-MS/MS Technique for Pharmacokinetic Drug–Drug Interactions of Selinexor with Posaconazole in Rats

open access: yesDrug Design, Development and Therapy, 2021
Background A method for the determination of selinexor by UPLC-MS/MS was established to study the effect of posaconazole on the pharmacokinetics of selinexor in rats.
Chen-jian Zhou   +5 more
semanticscholar   +1 more source

The Impact of Gelatin on the Pharmaceutical Characteristics of Fucoidan Microspheres with Posaconazole

open access: yesMaterials, 2021
Fungal infections and invasive mycoses, despite the continuous medicine progress, are an important globally therapeutic problem. Multicompartment dosage formulations (e.g., microparticles) ensure a short drug diffusion way and high surface area of drug ...
Marta Szekalska   +3 more
semanticscholar   +1 more source

Treatment of Aspergillosis. [PDF]

open access: yes, 2018
Infections caused by Aspergillus spp. remain associated with high morbidity and mortality. While mold-active antifungal prophylaxis has led to a decrease of occurrence of invasive aspergillosis (IA) in those patients most at risk for infection ...
Hoenigl, Martin, Jenks, Jeffrey D
core   +1 more source

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