Mechanoregulatory Effects of Cell‐Scale Microwells on Epithelial Cell Phenotype
In small polycaprolactone microwells, A549 epithelial cells span well edges, in contrast to cells growing on flat substrates. Focal adhesion sites (yellow) concentrate at topographic boundaries, while cytoskeletal tension (magenta stress fibers) is transmitted to the nucleus (blue), reducing nuclear sphericity.
Ruiwen He +10 more
wiley +1 more source
Implications of Nursing Peer Violence on Patient Safety: An Integrative Review. [PDF]
Fujii C, Iwasa Y.
europepmc +1 more source
MagPiezo enables wireless activation of endogenous Piezo1 channels without genetic modification using 19 nm magnetic nanoparticles and low‐intensity magnetic fields. It generates torque forces at the piconewton scale to trigger mechanotransduction in endothelial cells, standing as a novel platform to interrogate and manipulate Piezo1 activity in vitro.
Susel Del Sol‐Fernández +7 more
wiley +1 more source
Interrupting sedentary behaviour when working from home: a qualitative exploration of older desk-based employees. [PDF]
Mott L +4 more
europepmc +1 more source
Mechanically Stable and Tunable Photoactivated Peptide‐Based Hydrogels for Soft Tissue Adhesion
A collagen‐like peptide hydrogel platform is developed using supramolecular self‐assembly and light‐triggered crosslinking. It creates mechanically stable, tunable hydrogels with cytocompatibility and biodegradability, making them potential soft tissue adhesives.
Alex Ross +8 more
wiley +1 more source
Promoting vitality in a sheltered workplace: a realist evaluation protocol. [PDF]
Bom S, Hollaar M, Denktaş S, Kocken P.
europepmc +1 more source
xxxx. ABSTRACT Glioblastoma (GBM) remains one of the most lethal brain cancers, with median survival rarely exceeding 15 months after diagnosis. Interleukin‐12 (IL‐12) is a potent immunostimulatory cytokine capable of reshaping the tumor microenvironment (TME), yet its clinical translation is hindered by systemic toxicity and short half‐life. RNA‐based
Fatima Hameedat +11 more
wiley +1 more source
The Impact of Diversity Inclusion Practices in the Workplace Context: The Effect of Inclusive Leadership. [PDF]
Platania S, Maggio C, Boccadamo M.
europepmc +1 more source
Tissue Engineered Human Elastic Cartilage From Primary Auricular Chondrocytes for Ear Reconstruction
Despite over three decades of research, no tissue‐engineered solution for auricular reconstruction in microtia patients has reached clinical translation. The key challenge lies in generating functional elastic cartilage ex vivo. Here, we integrate synergistic cell‐biomaterial strategies to engineer auricular grafts with mechanical and histological ...
Philipp Fisch +13 more
wiley +1 more source
Predictors of Job Satisfaction of Frontline Staff Working in Supported Accommodation Services for People With Intellectual Disabilities. [PDF]
Humphreys L, Bigby C.
europepmc +1 more source

