Results 201 to 210 of about 1,927,312 (260)

Ecological diversification of sea catfishes is accompanied by genome-wide signatures of positive selection. [PDF]

Nat Commun
Rincon-Sandoval M, De-Kayne R, Shank SD, Pirro S, Ko'ou A, Abueg L, Tracey A, Mountcastle J, O'Toole B, Balacco J, Formenti G, Jarvis ED, Arcila D, Kosakovsky Pond SL, Davis A, Bloom DD, Betancur-R R.   +16 more
europepmc   +1 more source

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

FEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel, Carlos DeOcesano Pereira, Aline Ramos Maia Lobba, Melissa Regina Fessel, Ana Marisa Chudzinski‐Tavassi   +4 more
wiley   +1 more source

Positive Selection Drives the Evolution of the Structural Maintenance of Chromosomes (SMC) Complexes. [PDF]

Genes (Basel)
Forni D, Mozzi A, Sironi M, Cagliani R.
europepmc   +1 more source

Combined 5‐aminolevulinic acid and ferric ammonium citrate treatment promotes hair follicle growth by activating dermal papilla cells

FEBS Open Bio, EarlyView.
5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley   +1 more source

Positive Selection of TLR2 and MyD88 Genes Provides Insights Into the Molecular Basis of Immunological Adaptation in Amphibians. [PDF]

Ecol Evol
Zhang J, Zhao R, Bi H, He J, Guo Y, Liu D, Yang G, Chen X, Chen Z.   +8 more
europepmc   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

Impact of positive selection technology on seed yam productivity. [PDF]

Heliyon
Osei-Adu J, Aidoo R, Fialor SC, Ennin SA, Osei K, Asante BO, Danso-Abbeam G.   +6 more
europepmc   +1 more source

Signals of positive selection in genomes of palearctic Myotis-bats coexisting with a fungal pathogen. [PDF]

BMC Genomics
Twort VG, Laine VN, Field KA, Whiting-Fawcett F, Ito F, Reiman M, Bartonicka T, Fritze M, Ilyukha VA, Belkin VV, Khizhkin EA, Reeder DM, Fukui D, Jiang TL, Lilley TM.   +14 more
europepmc   +1 more source

Exploration on cold adaptation of Antarctic lichen via detection of positive selection genes. [PDF]

IMA Fungus
Wang Y, Zhang Y, Li R, Qian B, Du X, Qiu X, Chen M, Shi G, Wei J, Wei XL, Wu Q.   +10 more
europepmc   +1 more source

Whole-genome resequencing reveals positive selection and introgression signatures and genetic loci associated with early puberty traits in Chinese indigenous pigs. [PDF]

Genet Sel Evol
Cao M, Yuan T, Li D, Wang Y, Zhang L, Sun J, Lv G, Ding R, Yu T.   +8 more
europepmc   +1 more source