Results 211 to 220 of about 1,927,312 (260)
Enhanced Tolerance to Antifungals as a General Feature of Rho- Mutants in Yeast Species: Implications to Positive Selection of Respiratory Deficiency. [PDF]
MicroorganismsJohnson Z, Nadim F, Zubko MK.
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Genomic signatures of positive selection in Awarik dromedary camels from southwestern of Saudi Arabia. [PDF]
Front Vet SciAlmathen F.
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Positive Selection of Thymocytes
Annual Review of Immunology, 1995Differentiation of αβ T cell receptor (TCR)-expressing T cells involves an obligatory interaction with self-major histocompatibility complex (MHC) molecules in the thymus. This process, called positive selection, both rescues thymocytes from programmed cell death and induces their differentiation into mature T cells.
Stephen C Jameson +2 more
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Critical Reviews in Biotechnology, 2002
This review describes information concerning positive selection vectors on their mechanism, classification, property, and limitation. A total of 72 positive selection vectors collected were discussed. Positive selection vectors can reduce background and directly screen transformants containing cloned DNA fragments.
Byong H Lee
exaly +3 more sources
This review describes information concerning positive selection vectors on their mechanism, classification, property, and limitation. A total of 72 positive selection vectors collected were discussed. Positive selection vectors can reduce background and directly screen transformants containing cloned DNA fragments.
Byong H Lee
exaly +3 more sources
2004
The use of a new mode of selection-positive selection-has been demonstrated to be successful in a large variety of monocot and dicot species. This selection differs from more traditional modes of selection in which compounds such as antibiotics or herbicides are used to kill nontransformed cells (negative selection).
Allan, Wenck, Geneviève, Hansen
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The use of a new mode of selection-positive selection-has been demonstrated to be successful in a large variety of monocot and dicot species. This selection differs from more traditional modes of selection in which compounds such as antibiotics or herbicides are used to kill nontransformed cells (negative selection).
Allan, Wenck, Geneviève, Hansen
openaire +2 more sources
In favor of the selective model of positive selection
Seminars in Immunology, 1994The mechanisms of thymocyte commitment towards the CD4+ and CD8+ lineage remain unresolved. Two models--one based on instruction, the other on selection--have previously been proposed. The instructional model has been popularly received based on results of earlier studies.
Chan, Susan +2 more
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Science Signaling, 2012
Voltage-gated sodium channels enhance Ca 2+ influx in response to nonself ligands and promote the development of CD4 + T cells.
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Voltage-gated sodium channels enhance Ca 2+ influx in response to nonself ligands and promote the development of CD4 + T cells.
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Raf regulates positive selection
European Journal of Immunology, 1996AbstractT cell development is regulated by extracellular signals that mediate cellular proliferation and differentiation via specific signal transduction pathways. To determine the importance of the mitogen‐activated protein kinase (MAP kinase) pathway in thymocyte development, we analyzed transgenic mice expressing dominant negative Raf (DN Raf) and a
C C, O'Shea +4 more
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Current Opinion in Immunology, 1995
In the past year, significant technical developments have provided the opportunity to investigate the more mechanistic features of positive selection. Major progress has been made in determining the structure and function of the early pre-T cell receptor, in defining cell types that mediate positive selection, and in analyzing the contribution of MHC ...
B J, Fowlkes, E, Schweighoffer
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In the past year, significant technical developments have provided the opportunity to investigate the more mechanistic features of positive selection. Major progress has been made in determining the structure and function of the early pre-T cell receptor, in defining cell types that mediate positive selection, and in analyzing the contribution of MHC ...
B J, Fowlkes, E, Schweighoffer
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Genomic insights into positive selection
Trends in Genetics, 2006The traditional way of identifying targets of adaptive evolution has been to study a few loci that one hypothesizes a priori to have been under selection. This approach is complicated because of the confounding effects that population demographic history and selection have on patterns of DNA sequence variation.
Shameek, Biswas, Joshua M, Akey
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