Results 111 to 120 of about 15,388 (303)
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
On positivity preserving finite volume schemes for compressible Euler equations
, 1993 Positivity preserving property of first and higher order finite volume schemes for one and two dimensional compressible Euler equations of gas dynamics is considered.
Shu, Chi-Wang, Perthame, Benoit
core
Positivity-Preserving Rational Cubic Fractal Interpolation Function Together with Its Zipper Form
AxiomsIn this paper, a novel class of rational cubic fractal interpolation function (RCFIF) has been proposed, which is characterized by one shape parameter and a linear denominator.
Shamli Sharma +4 more
doaj +1 more source
Molecular Oncology, EarlyView.A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
Entropy dissipative higher order accurate positivity preserving time-implicit discretizations for nonlinear degenerate parabolic equations [PDF]
We develop entropy dissipative higher order accurate local discontinuous Galerkin (LDG) discretizations coupled with Diagonally Implicit Runge–Kutta (DIRK) methods for nonlinear degenerate parabolic equations with a gradient flow structure.
Xu, Yan +3 more
core +1 more source
Positivity-preserving and asymptotic preserving method for 2D Keller-Segal equations
Mathematics of Computation, 2017 We propose a semi-discrete scheme for 2D Keller-Segel equations based on a symmetrization reformation, which is equivalent to the convex splitting method and is free of any nonlinear solver. We show that, this new scheme is unconditionally stable as long as the initial condition does not exceed certain threshold, and it asymptotically preserves the ...
Jian-Guo Liu 0006, Li Wang, Zhennan Zhou
openaire +2 more sources
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Identification and data-driven model reduction of state-space representations of lossless and dissipative systems from noise-free data [PDF]
, 2011 We illustrate procedures to identify a state-space representation of a lossless- or dissipative system from a given noise-free trajectory; important special cases are passive- and bounded-real systems.
Trentelman, Harry +9 more
core +1 more source
Positivity-preserving interpolation of positive data by rational cubics
Journal of Computational and Applied Mathematics, 2008 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Hussain, Malik Zawwar, Sarfraz, Muhammad
openaire +1 more source
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source