Results 91 to 100 of about 3,919,087 (316)

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

Peter Lombard on God’s Knowledge and Its Capacities: Sententiae, Book I, Distinctions 38-39

open access: yesSententiae, 2018
The global Peter Lombard research reinaugurated in 1990s has resulted in a number of recent publications, but the Master of the Sentences’ theology proper is partially underreseached. In particular, a more detailed exposition of the distinctions 35-41 of
Rostislav Tkachenko
doaj   +1 more source

(IM)POSSIBILITY OF FORGIVENESS?

open access: yes, 2017
Intro -- Publication Acknowledgement -- Editor's Foreword -- Dedication -- Acknowledgements -- 1 The (im)possibility of forgiveness? -- 2 Theoretical underpinnings I -- 3 Theoretical underpinnings II -- 4 An exegetical reading of Matthew 18.15-35 -- 5 ...
DION FORSTER.
core  

Conceivability, Apriority and Modality [PDF]

open access: yes, 2011
I aim to understand whether apriority entails necessity, aposteriority entails contingency and conceivability entails possibility; that is, the relationship between, and the nature of, rationality and modality.
WINSTANLEY, PAUL
core  

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

The Dialectic of Sin and Faith in “Being Able to be Oneself”

open access: yesOpen Theology, 2019
Kierkegaard understands the human self as a process of becoming that is situated in a dialectical relation between sin and faith. The chief task of each human being is to become a true self, instead of assuming a fraudulent identity.
Zunic Nikolaj
doaj   +1 more source

Edge cases as academic possibility [PDF]

open access: yes, 2018
What are edge cases, and why do they matter? Dr James O’Sullivan, a digital arts and humanities lecturer at University College Cork, puts flippancy aside to unpick these uncanny constructs that are born of digital apparatus and reside somewhere between ...
O'Sullivan, James
core  

Biophysical approaches for studying viral entry

open access: yesFEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

Insight Problem Solving: A Critical Examination of the Possibility of Formal Theory

open access: yes, 2012
This paper provides a critical examination of the current state and future possibility of formal cognitive theory for insight problem solving and its associated “aha!” experience.
Batchelder, William H.   +1 more
core   +1 more source

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