Results 101 to 110 of about 9,087,077 (299)
The Dialectic of Sin and Faith in “Being Able to be Oneself”
Kierkegaard understands the human self as a process of becoming that is situated in a dialectical relation between sin and faith. The chief task of each human being is to become a true self, instead of assuming a fraudulent identity.
Zunic Nikolaj
doaj +1 more source
Structural biology of ferritin nanocages
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Electronic inhomogeneity in EuO: Possibility of magnetic polaron states
We have observed the spatial inhomogeneity of the electronic structure of a single-crystalline electron-doped EuO thin film with ferromagnetic ordering by employing infrared magneto-optical imaging with synchrotron radiation.
A. K. Zvezdin +13 more
core +1 more source
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Reconstructive Possibilities [PDF]
Gabriel, Djedovic +2 more
openaire +2 more sources
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
AbstractThis chapter starts out from the idea that semantics is a “special science” whose aim, like that of chemistry or ecology, is to identify systematic, high-level patterns in a fundamentally physical world. I defend an approach to this task on which sentences are associated with sets of possible worlds (of some kind). These sets of worlds, however,
openaire +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Opening Spaces of Possibility: The Enactive as a Qualitative Research Approach
In this jointly written article, reflexivity and subjectivity in qualitative research are addressed through an enactive view/approach incorporating embodied knowing.
Johnna Haskell +2 more
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