Results 111 to 120 of about 4,504,294 (307)

Opening Spaces of Possibility: The Enactive as a Qualitative Research Approach

open access: yesForum: Qualitative Social Research, 2002
In this jointly written article, reflexivity and subjectivity in qualitative research are addressed through an enactive view/approach incorporating embodied knowing.
Johnna Haskell   +2 more
doaj  

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

The microbiome in human skin aging

open access: yesFEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana   +3 more
wiley   +1 more source

Evaluation to possibility of attending U.N. for Taiwan

open access: yes, 2015
Evaluation to possibility of attending U.N. for TaiwanEvaluation to possibility of attending U.N. for Taiwanåéæ·¡æ°´æ ¡å20080310ç´æ¬
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core  

Rola negacji w opisie świata według arystotelesowskiej Metafizyki [PDF]

open access: yesArgument, 2012
The notions of „being” and „non-being” have entered philosophical language, forming thebasis of ontology and meontology, as the counterparts of the Greek expressions to o]n and tomh o]n (nominalised forms, affirmative and negative, of the participle of ...
Jan BIGAJ
doaj  

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

open access: yesFEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança   +2 more
wiley   +1 more source

On Intersectoral Asymmetries in Factors Substitutability “Equilibrium Production Possibility Frontiers” and the emergence of indeterminacies [PDF]

open access: yes
The existence of asymmetries in factors substitutability between the distinct sectors of a given economy will directly rule the influence that spillover effects have upon its determinacy properties.
Jean-Pierre Drugeon
core  

Tetractys of philosophical health : A structured approach to aligning personal cosmology, higher purpose, and practices of the compossible

open access: yes
This article introduces the Tetractys of Philosophical Health, a structured visual exercise inspired by the Pythagorean tetractys that facilitates alignment between an individual’s cosmological worldview, sense of purpose, and practical engagement with ...
de Miranda, Luis, de Miranda, Luis,
core   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

open access: yesFEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk   +11 more
wiley   +1 more source

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