Results 141 to 150 of about 7,087,684 (332)

Pharmacokinetics of dolutegravir, tenofovir and lamivudine during venous–venous extracorporeal membrane oxygenation (VV‐ECMO): A case report

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
While providing potentially life‐saving cardiorespiratory support for critically ill patients, extracorporeal membrane oxygenation (ECMO) may detrimentally affect pharmacokinetic (PK) performance and concurrent drug efficacy and safety. We describe a patient with Pneumocystis jirovecii pneumonia (PJP) in the context of acquired immunodeficiency ...
Tom C. Zwart   +7 more
wiley   +1 more source

Exposure to different severities of famine and subsequent risk of sarcopenia in old age

open access: yesJournal of Nutritional Oncology
. Background. Poor nutritional status is closely related to the development of sarcopenia and possible sarcopenia. Limited articles have evaluated the impact of undernutrition at different stages of life on the development of sarcopenia or possible ...
Miao-Miao Lu, Yu-Wei Zhou, Xi Jin
doaj   +1 more source

An Alternative Aproach of Exercise Prescription for Type 2 Diabetes Control in Time and Space Restrictions

open access: yesChronic Diseases and Translational Medicine, EarlyView.
Continuum of physical behavior changes and important questions about exercise prescription approach in the diabetes context. ABSTRACT Although physical exercise is widely recognized for its role in glycemic control and overall health, population characteristics such as comorbidities, sedentary behavior, disease‐related complications, and socioeconomic ...
Rodrigo Sudatti Delevatti   +2 more
wiley   +1 more source

Association between sarcopenia and multimorbidity among middle-aged and older adults in China: Findings from the China Health and Retirement Longitudinal Study

open access: yesExperimental Gerontology
Background: Little is known about the association between sarcopenia and multimorbidity among middle-aged and older adults. This study investigated whether sarcopenia is associated with multimorbidity in middle-aged and older Chinese individuals ...
Mingming Deng   +4 more
doaj   +1 more source

Pancreas Cancer-Associated Weight Loss. [PDF]

open access: yes, 2019
Unintentional weight loss in patients with pancreatic cancer is highly prevalent and contributes to low therapeutic tolerance, reduced quality of life, and overall mortality.
Denlinger, Crystal S   +7 more
core  

Fat mass limits lower-extremity relative strength and maximal walking performance in older women [PDF]

open access: yes, 2011
The purpose of this study was to determine if excess fat negatively affects relative strength and walking gait performance in overweight, older women. Twenty five older women (65 – 80 yr) were separated into normal weight (BMI \u3c 25 kg m−2 , n=11) and ...
Kralian, Rachel J.   +2 more
core   +2 more sources

Frailty and Cardiovascular Events as Determined by Body Composition: A Systematic Review

open access: yesChronic Diseases and Translational Medicine, EarlyView.
Frailty phenotypes and risk of cardiovascular disease. Sarcopenic obese phenotype is associated with increased prevalence of cardiovascular risk factors and progression of metabolic syndrome, leading to cardiovascular events and cardiovascular mortality, while the Anorexic malnourished phenotype is associated with reduced prevalence of cardiovascular ...
Ishleen Oberoi   +5 more
wiley   +1 more source

Modulation of PGC-1α activity as a treatment for metabolic and muscle-related diseases [PDF]

open access: yes, 2014
Physical inactivity is a predisposing factor for various disease states including obesity, cardiovascular disease, as well as for certain types of cancer. Regular endurance exercise mediates several beneficial effects such as increased energy expenditure
Handschin, Christoph   +1 more
core   +1 more source

Cardiovascular‐Kidney‐Metabolic Syndrome in People With HIV: An Emerging Frontier for Clinical Pharmacology

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
As antiretroviral therapy (ART) prolongs lifespans, people with HIV (PWH) face a new syndemic: Cardiovascular‐Kidney‐Metabolic (CKM) syndrome. Yet CKM in PWH is poorly characterized. Inflammation, complex pharmacokinetic (PK) alterations, ART‐associated metabolic effects, and gut dysbiosis amplify risk. Managing CKM increases medication burden, thereby
Aaron S. Devanathan, Thomas D. Nolin
wiley   +1 more source

A co-created intervention with care home residents and university students following a service-learning methodology to reduce sedentary behaviour: the GET READY project protocol [PDF]

open access: yes, 2018
Background: There is a growing demand for long-term care settings. Care-home residents are a vulnerable group with high levels of physical dependency and cognitive impairment.
Chastin, Sebastien   +5 more
core   +3 more sources

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