Results 91 to 100 of about 95,371 (247)

Acute effects of rapid versus sustained isometric contraction durations on countermovement jump performance in national level young male soccer players

Scientific Reports
This study investigated the effects of different distributions of isometric conditioning activity (ICA) within a single set—1 s contraction performed 9 repetitions (RAPID) versus 3 s contractions performed 3 repetitions (SUST)—on countermovement jump ...
Wojciech Grzyb, Jakub Jarosz
doaj   +1 more source

A comparison of three post-activation potentiation enhancement warm up strategies on bench press performance

Frontiers in Sports and Active Living
BackgroundAt loads greater than 80% of one repetition maximum in bench press, at the ascending phase of the movement, the barbell decelerates or stops for a short time before it accelerates again during a region named sticking region.
Yousef Hedayati, Roland van den Tillaar
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Is There a Post-Activation Performance Enhancement of a Conditioning Activity on a High-Velocity Movement in a Different Biomechanical Plane of Motion

The aim of this study was to investigate the potentiation effect of a conditioning activity (CA) on a high velocity movement (HVM) that occurs in a different biomechanical plane.
Parks, Austin
core   +1 more source

Self-enhancement: food for thought

, 2008
Self-enhancement denotes a class of psychological phenomena that involve taking a tendentiously positive view of oneself. We distinguish between four levels of self-enhancement—an observed effect, an ongoing process, a personality trait, and an ...
Sedikides, Constantine, Gregg, Aiden P.
core   +1 more source

Effects of strength training on repeated sprint ability in team sports players: a systematic review [PDF]

PeerJ
Objective This systematic review was conducted to analyze the existing evidence on the effects of strength training (ST) and complex/contrast training (CCT) on repeated sprint ability (RSA) in team sports players.
Andrés Osses-Rivera, Rodrigo Yáñez-Sepúlveda, Sebastián Jannas-Vela, Jeppe F. Vigh-Larsen, Matías Monsalves-Álvarez   +4 more
doaj   +2 more sources

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

Personalized warm-up strategies for adult athletes: a meta-analysis based on athletic level, gender, and region

Frontiers in Physiology
ObjectiveThis study aimed to investigate the acute effects of high-intensity parallel squats (HIPS) on lower-limb explosive power in adult athletes, with a specific focus on how athletic calibre, sex and geographic origin modulate the ensuing ...
Ye Xu, Jianmin Dai, Xingyue Liang, Yurou Zhang   +3 more
doaj   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Sex-moderated Post-activation Performance Enhancement in Trained Individuals

The primary aim of this study will be to investigate sex as a moderating factor on countermovement jump (CMJ) post-activation performance enhancement (PAPE) outcomes using potentiation protocols of different intensities.
Alec Piñero, Brad Jon Schoenfeld
core   +1 more source