Results 131 to 140 of about 14,728,127 (259)

Reviewing the performance and investment practices of the Kansas Public Employees Retirement System

open access: yes, 1998
"A report to the Legislative Post Audit Committee"--Cover.; "January 1998" ...
Clarke, Chris.
core  

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

open access: yesMolecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou   +4 more
wiley   +1 more source

Self-enhancement: food for thought

open access: yes, 2008
Self-enhancement denotes a class of psychological phenomena that involve taking a tendentiously positive view of oneself. We distinguish between four levels of self-enhancement—an observed effect, an ongoing process, a personality trait, and an ...
Sedikides, Constantine, Gregg, Aiden P.
core   +1 more source

NAPRT loss promotes lung tumor initiation and growth through AKT signaling independently of NAD+ biosynthesis

open access: yesMolecular Oncology, EarlyView.
Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh   +11 more
wiley   +1 more source

Effects of Traditional and Velocity-Based Designed Post Activation Performance Enhancement Interventions on Agility Performance

open access: yesInternational Journal of Disabilities Sports and Health Sciences
The aim of the study was to examine the effects of post-activation performance enhancement interventions designed with traditional strength training and velocity-based training on agility performance. The study was completed in three experimental sessions with 20 male participants (age;18.10±0.71 years, height;179±6.13 cm, weight:73.25±6.80 kg ...
Sümeyye Genç   +2 more
openaire   +1 more source

Private-sector input : ways to foster such input if the Kansas Performance Review Board is abolished

open access: yes, 2001
Cover title.; "A report to the Legislative Post Audit Committee."; "March 2001 ...
Murdie, Laurel.
core  

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

open access: yesMolecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico   +5 more
wiley   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

open access: yesMolecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez   +5 more
wiley   +1 more source

Effect of PAPE induced by different squat loads on jump performance in collegiate female basketball players

open access: yesBMC Sports Science, Medicine and Rehabilitation
Background Post-activation performance enhancement (PAPE) effectively augments explosive performance, especially in jumping. As female athletes have distinct neuromuscular and biomechanical traits that may affect the PAPE response, the optimal squat load
Xu Si   +4 more
doaj   +1 more source

Can Complex Training Improve Acute and Long-Lasting Performance in Basketball Players? A Systematic Review

open access: yesApplied Sciences
Basketball demands a sophisticated blend of tactical, technical, physical, and psychological skills, and various methods have been proposed to prepare players for these demands, including resistance training to enhance strength, power, speed, agility ...
Enrique Flórez Gil   +4 more
doaj   +1 more source

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