Results 121 to 130 of about 14,728,127 (259)
Background The post-activation performance enhancement (PAPE) effect has been widely studied; however, its repeatability across training sessions during the competitive season in team sports has not yet been verified.
Jakub Jarosz +6 more
doaj +1 more source
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
The purpose of this study was to investigate the acute effects of a mini-band PAPE protocol on CMJ height in female basketball players and to determine whether this effect varies across different playing positions.
Çağdaş Özgür Cengizel
doaj +1 more source
Spatial biology in cancer epigenetics
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
BackgroundThe present study set out to ascertain the effects of combined exercises, consisting of resistance training and plyometric exercises at varying degrees of intensity, on biochemical and respiratory parameters in female volleyball players ...
Korhan Kavuran +7 more
doaj +1 more source
Kansas Soldiers Home [1985 performance audit]
"A Report to the Legislative Post Audit Committee"--Cover.; "April 1985 ...
Racine, Trudy.
core
ADP‐ribosylation: An emerging regulator of the epigenome
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho +2 more
wiley +1 more source
International Journal of Exercise Science 17(4): 154-171, 2024. The purpose of this study was to evaluate the effectiveness of implementing task-specific, post-activation performance enhancement (PAPE) strategies, to acutely improve Army Combat Fitness Test (ACFT) performance.
Bonilla, Christopher +4 more
openaire +2 more sources
"A report to the Legislative Post Audit Committee"--Cover.; "May 1993" ...
Berberich Trahan & Co.
core
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee +3 more
wiley +1 more source

