Results 101 to 110 of about 67,475 (271)

Tonic and phasic nitric oxide signals in hippocampal long-term potentiation

, 2006
Nitric oxide ( NO) participates in long-term potentiation (LTP) and other forms of synaptic plasticity in many different brain areas but where it comes from and how it acts remain controversial.
Hopper, RA, Garthwaite, J
core  

Eccentric flywheel post-activation potentiation influences swimming start performance kinetics [PDF]

, 2019
This study aimed to assess the effects of post-activation potentiation in the strength related variables of a kick start. Thirteen competitive swimmers performed three kick starts after a standardized warm up (denoted USUAL) and another after inducing ...
Cuenca Fernández, Francisco, de Jesus, Kelly, de Jesus, Karla, Arellano Colomina, Raúl, Zacca, Rodrigo, Vilas-Boas, João Paulo, Fernandes, Ricardo J, López Contreras, Gracia, Mourão, Luis   +8 more
core   +1 more source

Acute enhancement strategies for countermovement jump performance: a network meta-analysis of different resistance training protocols

Frontiers in Physiology
BackgroundCountermovement jump performance is the gold standard for assessing lower limb power, and even minor improvements can significantly enhance performance in sports such as basketball and volleyball.
Ying Zhou, Ying Zhou, Kaiming Wen, Yulong Sun   +3 more
doaj   +1 more source

LMO7 Suppresses Tumor‐Associated Macrophage Phagocytosis of Tumor Cells Through Degradation of LRP1

Advanced Science, EarlyView.
LMO7 in tumor‐associated macrophages suppresses phagocytosis of tumor cells and limits cytotoxic T lymphocytes infiltration, fostering tumor progression. Mechanistically, LMO7 mediates the ubiquitination and degradation of the phagocytic receptor LRP1, impairing its ability to engulf tumor cells and driving macrophages toward an antitumor phenotype ...
Mengkai Li, Tao Wang, Yuwen Zhong, Zhiming Wang, Wei Li, Zejian Wang, Xinyi Yang, Yu Qiao, Jianfeng Xiang, Wei Gu, Zishu Wang, Lei Sun, Feng Qian   +12 more
wiley   +1 more source

Intracellular ATP influences synaptic plasticity in area CA1 of rat hippocampus via metabolism to adenosine and activity-dependent activation of adenosine A1 receptors [PDF]

, 2011
The extent to which brain slices reflect the energetic status of the in vivo brain has been a subject of debate. We addressed this issue to investigate the recovery of energetic parameters and adenine nucleotides in rat hippocampal slices and the ...
D. Grahame Hardie, Hardie, D. G. (D. Grahame), Naomi Pentland, Simon Hawley, Frenguelli, Bruno, Doney, Alexander S., Pentland, Naomi, Frenguelli, Bruno G., Stephanie zur Nedden, Hawley, Simon, Alexander S. Doney, Bruno G. Frenguelli, Hardie, D. Grahame, Doney, Alexander S.; id_orcid, Zur Nedden, Stephanie   +14 more
core   +1 more source

Considering the Effects of Upper Body, Lower Body, and Their Combination on Post-Activation Performance Enhancement of Bowling Velocity Among Amateur Cricket Players

Physical Education Theory and Methodology
Objectives. This study aimed to investigate the effects of post-activation performance enhancement on bowling velocity among amateur cricket players using multiple interventions as conditioning activities focusing on the upper body, lower body, and a ...
Bhargav Sarmah, Nishanta Bordoloi, Pushpendra Narvariya, Rohit Kumar Thapa   +3 more
doaj   +1 more source

Marburg Virus Glycoprotein Is a Remarkable Virulent Factor Linked to Hemorrhagic Pathology: Evidence from Multimodal Experimental Systems

Advanced Science, EarlyView.
By integrating data from in vitro, ex vivo, and in vivo models, our research identifies the MARV glycoprotein as a remarkable hemorrhagic factor, filling a major gap in this important field. It also provides practical experimental tools for the basic research on viral pathogenesis and applied research aimed at antiviral intervention for hemorrhagic ...
Ting Yao, Hang Liu, Yanfeng Yao, Wei Deng, Jiawen Sun, Zhenyu Kang, Ashaq Ali, Chao Shan, Zhiming Yuan, Fei Deng, Hualin Wang, Yun‐Jia Ning   +11 more
wiley   +1 more source

Engineering Osteoimmune Responses with Functionalized Orthopedic Implants for Post‐Operative Osteosarcoma Treatment

Advanced Science, EarlyView.
Osteosarcoma is the most common primary bone tumor with limited treatment options and a terrible prognosis. This review provides a comprehensive summary of the recent development of osteoimmunomodulatory implants for post‐operative osteosarcoma treatment, of which the potential utility in evoking durable anti‐osteosarcoma immunity and accelerating bone
Yilong Dong, Lingshuang Wang, Hui Zhang, Menghuan Li, Zhong Luo, Yan Hu, Chunyuan Cai   +6 more
wiley   +1 more source

GATA4‐Driven Transcription of HtrA1 Promotes Cellular Senescence in Ménière's Disease and Age‐Related Audio‐Vestibular Dysfunction

Advanced Science, EarlyView.
This study identifies the HDAC6/GATA4/HtrA1 axis as a critical driver of cellular senescence in the inner ear. GATA4 nuclear translocation, facilitated by HDAC6 downregulation, transcriptionally activates HtrA1, promoting hair cell senescence, SASP, and audio‐vestibular dysfunction in models of Ménière's disease and age‐related audio‐vestibular ...
Na Zhang, Na Li, Yan Wang, Jing Zhang, Jiahui Liu, Lei Chen, Yongdong Song, Yurong Mu, Yuechen Han, Yafeng Lyu, Xiaofei Li, Hanyue Wang, Jing Wang, Yao Lu, Zhaomin Fan, Daogong Zhang, Haibo Wang   +16 more
wiley   +1 more source

Role of mast cell- and non-mast cell-derived inflammatory mediators in immunologic induction of synaptic plasticity

Brazilian Journal of Medical and Biological Research, 1997
We have previously discovered a long-lasting enhancement of synaptic transmission in mammal autonomic ganglia caused by immunological activation of ganglionic mast cells.
A.A.C. Albuquerque, J.H. Leal-Cardoso, D. Weinreich   +2 more
doaj   +1 more source