Results 41 to 50 of about 11,445,582 (287)

Espaço inventado: o teatro pós-dramático na escola Invented space: postdramatic theater at school

open access: yesEducação em Revista, 2008
Com a publicação da lei n. 9394/96, a arte integra-se ao currículo do ensino básico como área de conhecimento. Neste ensaio, problematiza-se essa nova condição da arte na escola, refletindo a particularidade da experiência artística em relação às outras ...
Carminda Mendes André
doaj   +1 more source

Successful endoscopic management for early manifested postcesarean section uretero-uterine fistula: A case report and literature review

open access: yesUrology Annals, 2022
We report a rare case of post-cesarian section uretero-uterine fistula (UUF) in a 36 years old female who presented on a postoperative day 5 with paradoxical urine incontinence and occasional normal urethral voiding.
Adel Elatreisy   +4 more
doaj   +1 more source

Comparing the paths of Hedgehog release in artificial and natural settings

open access: yesFEBS Letters, EarlyView.
Hh morphogens require solubilization factors to overcome their tight association with the plasma membrane and signal to distant cells, but the precise functions of these factors are controversial. Here, we use published in vivo observations as the most relevant evidence to test their suggested functions and discuss contradictions and gaps between in ...
Janna Puschmann, Kay Grobe
wiley   +1 more source

Fictionality of Heiner Muller’s Drama: Forms and Functions

open access: yesНаучный диалог, 2019
Using the broad material of Heiner Müller’s drama (1929-1995), the question of how to destroy the classical forms of dramatic conventions in German drama of the 60-80s is discussed in the article.
N. E. Seibel
doaj   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

Neuro-Dramatic-Play and a hero’s journey [PDF]

open access: yes, 2020
This chapter aims to consider the principles of neuro-dramatic play - NDP (Jennings 2011) as a form of pre-therapy/ structured interventional play. By running nine sessions with a group of 15 children (Years 3 to 6, 7-11 year olds), all of whom had been ...
Clive Holmwood
core   +1 more source

Games and Stakes in Samuel Beckett’s Plays (1906-1989) [PDF]

open access: yesUirtus
This article analyses the thematic, semantic and aesthetic dimensions of games and their interactions in the composition of Samuel Beckett’s theatrical art.
Ousmane Aly Pame
doaj   +1 more source

Regulation of Deubiquitinating Enzymes by Post-Translational Modifications

open access: yesInternational Journal of Molecular Sciences, 2020
Ubiquitination and deubiquitination play a critical role in all aspects of cellular processes, and the enzymes involved are tightly regulated by multiple factors including posttranslational modifications like most other proteins.
Tanuza Das, S. Shin, E. J. Song, E. Kim
semanticscholar   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

open access: yesMolecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault   +12 more
wiley   +1 more source

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