Results 41 to 50 of about 1,840 (204)
O estudo discute a relação entre os processos comunicacionais e as interlocutivas possibilidades de interpretação a partir da mudança de meio de manifestação onde a arte está inserida, questionando a autonomia da releitura como uma obra autônoma.
Marina Mentz, Sarai Patricia Schmidt
doaj +5 more sources
Performing the Theatricality in the Game of Framings: rethinking the weaving of the dramatic
Through the analysis of contemporary propositions and postulating the game of framings as the principle of scene poetics building, this article analyzes the notions of theatricality and performativity as co-existing functions.
Rejane Arruda (Universidade Vila Velha ‒ UVV, Vila Velha/ES, Brazil)
doaj
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Performing the Theatricality in the Game of Framings: rethinking the weaving of the dramatic
Through the analysis of contemporary propositions and postulating the game of framings as the principle of scene poetics building, this article analyzes the notions of theatricality and performativity as co-existing functions. Displaced from the field of
Rejane Arruda
doaj
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
The theatrical praxis and its visual roots: Sarah Kane, Maurice Maeterlinck and the Post-Dramatic
This article discusses probable visual roots for theatrical praxis. I observed derivations originating in the Greek verb théa, as well as in the noun theatron, found in ancient Greece. Starting from this context, I identified theoretical links with Hans-Thies Lehmann, Peter Szondi and Ewald Hackler.
openaire +1 more source
MITF maintains genome stability in nonmelanocyte lineages
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
William Szekspir w postpamięciowym dyskursie o zagładzie
The aim of the paper is to discuss the role of literary output of William Shakespeare in post‑memorial discourse about Holocaust. It analyzes various culture texts (film and theater adaptations, memoirs, essays and short stories) devoted to Holocaust ...
Agata Dąbrowska
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The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Jan Klata is a director who has been labelled a provocateur and who is considered to hold nothing cultural or national sacred. From the beginning of his artistic career he is said to have challenged authorities: theatrical, ethnic, national, etc.
Jacek Fabiszak
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