Results 101 to 110 of about 6,144,891 (238)
Frontiers in Cellular and Infection MicrobiologyIntroductionInnate immune response to Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infection activates multiple interferon stimulated genes (ISGs), including ADAR1 p150 isoform, which edits adenosine (A) residues within double stranded ...
Aiswarya Mukundan Nair +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
Molecular Oncology, EarlyView.The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
wiley +1 more source
-ing words in RBMT: multilingual evaluation and exploration of pre- and post-processing solutions [PDF]
, 2010 This PhD dissertation falls within the domain of machine translation and it specifically focuses on the machine translation of IT-domain -ing words into four target languages: French, German, Japanese and Spanish.
Aranberri Monasterio, Nora
core +2 more sources
The Current Status of Translation Training and MTPE Training of MTI Students in China
Estudis Filologics i de TraduccióThe training of Master of Translation and Interpreting (MTI) students in China is crucial given the rising global need for professional translators.
Zihui Qin +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
Perception vs Reality: Measuring Machine Translation Post-Editing Productivity
, 2014 This paper presents a study of user-perceived vs real machine translation (MT) post-editing effort and productivity gains, focusing on two bidirectional language pairs: English— German and English—Dutch.
Gaspari F +4 more
core
Seamlessly Editing the Web [PDF]
, 2010 The typical process of editing content on the web is strongly moded. Authors are forced to switch between editing and previewing and publishing modes before, during, and after the editing process. This thesis explores a new paradigm of editing content on
Novak, Brook Jesse
core
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source