Results 91 to 100 of about 6,144,891 (238)
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
The use of automation in the rendition of certain articles of the Saudi Commercial Law into English: a post-editing-based comparison of five machine translation systems. [PDF]
Front Artif Intell, 2023 Alwazna RY.
europepmc +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Towards Predicting Post-editing Effort with Source Text Readability
JoSTrans: The Journal of Specialised TranslationThis paper investigates the impact of source text readability on the effort of post-editing English-Chinese Neural Machine Translation (NMT) output.
Guangrong Dai, Siqi Liu
doaj +1 more source
Translating in the Cloud Age: Online Marketplaces
Hermes, 2017 This article explores the influence of cloud computing on translation, including professional translation. Cloud computing reshapes the management of labour in ways that unsettle the traditional relations between managers and workers.
Ignacio Garcia
doaj +1 more source
Molecular Oncology, EarlyView.Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens +6 more
wiley +1 more source
Literary Post-editing and the Question of Copyright
HermesTranslation poses a challenge to copyright laws, which extend protection to works based on the originality of expression rather than the ideas expressed, because translations convey the ideas of the original in a different language and therefore also ...
Kristiina Taivalkoski-Shilov +1 more
doaj +1 more source
A review of the state-of-the-art in automatic post-editing. [PDF]
Mach Transl, 2021 do Carmo F +8 more
europepmc +1 more source
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source