Transcriptional and Post-Transcriptional Regulation of Autophagy [PDF]
Cells, 2022 Autophagy is a widely conserved process in eukaryotes that is involved in a series of physiological and pathological events, including development, immunity, neurodegenerative disease, and tumorigenesis.
Qiuqin Ma +5 more
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Post-transcriptional regulation of erythropoiesis [PDF]
Blood Science, 2023 Erythropoiesis is a complex, precise, and lifelong process that is essential for maintaining normal body functions. Its strict regulation is necessary to prevent a variety of blood diseases.
Yanan Li +5 more
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Post-transcriptional regulation of the transcriptional apparatus in neuronal development [PDF]
Frontiers in Molecular NeurosciencePost-transcriptional mechanisms, such as alternative splicing and polyadenylation, are recognized as critical regulatory processes that increase transcriptomic and proteomic diversity.
Mohammad Nazim
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Transcriptional and Post-transcriptional Gene Regulation by Long Non-coding RNA [PDF]
Genomics, Proteomics & Bioinformatics, 2017 Advances in genomics technology over recent years have led to the surprising discovery that the genome is far more pervasively transcribed than was previously appreciated.
Iain M. Dykes, Costanza Emanueli
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Transcriptional and post-transcriptional regulation of young genes in plants [PDF]
BMC Biology, 2022 Background New genes continuously emerge from non-coding DNA or by diverging from existing genes, but most of them are rapidly lost and only a few become fixed within the population.
Vivek Kumar Raxwal +3 more
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Post-transcriptional regulation in early cell fate commitment of germ layers [PDF]
BMC GenomicsBackground Cell differentiation during development is orchestrated by precisely coordinated gene expression programs. While some regulatory mechanisms are well understood, there is a significant room to explore unresolved aspects of lineage choice and ...
Rubens Gomes-Júnior +6 more
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Iron-mediated post-transcriptional regulation in Toxoplasma gondii. [PDF]
PLoS PathogensIron is required to support almost all life; however, levels must be carefully regulated to maintain homeostasis. Although the obligate parasite Toxoplasma gondii requires iron, how it responds upon iron limitation has not been investigated.
Megan A Sloan +4 more
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Novel Insights into the Molecular Mechanisms Governing Embryonic Epicardium Formation
Journal of Cardiovascular Development and Disease, 2023 The embryonic epicardium originates from the proepicardium, an extracardiac primordium constituted by a cluster of mesothelial cells. In early embryos, the embryonic epicardium is characterized by a squamous cell epithelium resting on the myocardium ...
Rita Carmona +6 more
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Prokineticin-Receptor Network: Mechanisms of Regulation
Life, 2022 Prokineticins are a new class of chemokine-like peptides that bind their G protein-coupled receptors, PKR1 and PKR2, and promote chemotaxis and the production of pro-inflammatory cytokines following tissue injury or infection.
Roberta Lattanzi, Rossella Miele
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Designing Lentiviral Vectors for Gene Therapy of Genetic Diseases
Viruses, 2021 Lentiviral vectors are the most frequently used tool to stably transfer and express genes in the context of gene therapy for monogenic diseases. The vast majority of clinical applications involves an ex vivo modality whereby lentiviral vectors are used ...
Valentina Poletti, Fulvio Mavilio
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