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Post-transcriptional regulation of erythropoiesis [PDF]

open access: yesBlood Science, 2023
Erythropoiesis is a complex, precise, and lifelong process that is essential for maintaining normal body functions. Its strict regulation is necessary to prevent a variety of blood diseases.
Yanan Li   +5 more
doaj   +2 more sources

Transcriptional and Post-transcriptional Gene Regulation by Long Non-coding RNA [PDF]

open access: yesGenomics, Proteomics & Bioinformatics, 2017
Advances in genomics technology over recent years have led to the surprising discovery that the genome is far more pervasively transcribed than was previously appreciated.
Iain M. Dykes, Costanza Emanueli
doaj   +6 more sources

Post-transcriptional regulation of the transcriptional apparatus in neuronal development [PDF]

open access: yesFrontiers in Molecular Neuroscience
Post-transcriptional mechanisms, such as alternative splicing and polyadenylation, are recognized as critical regulatory processes that increase transcriptomic and proteomic diversity.
Mohammad Nazim
doaj   +2 more sources

Iron-mediated post-transcriptional regulation in Toxoplasma gondii. [PDF]

open access: yesPLoS Pathogens
Iron is required to support almost all life; however, levels must be carefully regulated to maintain homeostasis. Although the obligate parasite Toxoplasma gondii requires iron, how it responds upon iron limitation has not been investigated.
Megan A Sloan   +4 more
doaj   +2 more sources

Novel Insights into the Molecular Mechanisms Governing Embryonic Epicardium Formation

open access: yesJournal of Cardiovascular Development and Disease, 2023
The embryonic epicardium originates from the proepicardium, an extracardiac primordium constituted by a cluster of mesothelial cells. In early embryos, the embryonic epicardium is characterized by a squamous cell epithelium resting on the myocardium ...
Rita Carmona   +6 more
doaj   +1 more source

Transcriptional and Post-Transcriptional Regulation of Autophagy

open access: yesCells, 2022
Autophagy is a widely conserved process in eukaryotes that is involved in a series of physiological and pathological events, including development, immunity, neurodegenerative disease, and tumorigenesis.
Qiuqin Ma   +5 more
doaj   +1 more source

Prokineticin-Receptor Network: Mechanisms of Regulation

open access: yesLife, 2022
Prokineticins are a new class of chemokine-like peptides that bind their G protein-coupled receptors, PKR1 and PKR2, and promote chemotaxis and the production of pro-inflammatory cytokines following tissue injury or infection.
Roberta Lattanzi, Rossella Miele
doaj   +1 more source

A Quarter Century History of ATML1 Gene Research

open access: yesPlants, 2021
The cloning of the ATML1 gene, encoding an HD-ZIP class IV transcription factor, was first reported in 1996. Because ATML1 mRNA was preferentially detected in the shoot epidermis, cis-regulatory sequences of ATML1 have been used to drive gene expression ...
Hiroyuki Iida, Shinobu Takada
doaj   +1 more source

Designing Lentiviral Vectors for Gene Therapy of Genetic Diseases

open access: yesViruses, 2021
Lentiviral vectors are the most frequently used tool to stably transfer and express genes in the context of gene therapy for monogenic diseases. The vast majority of clinical applications involves an ex vivo modality whereby lentiviral vectors are used ...
Valentina Poletti, Fulvio Mavilio
doaj   +1 more source

Regulation of Doublesex1 Expression for Environmental Sex Determination in the Cladoceran Crustacean Daphnia

open access: yesFrontiers in Cell and Developmental Biology, 2022
The cladoceran crustacean Daphnia produces only females by parthenogenesis in a healthy population. However, in response to environmental declines such as crowding and lack of foods, it produces eggs destined to become males that are genetically ...
Yasuhiko Kato, Hajime Watanabe
doaj   +1 more source

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