Results 31 to 40 of about 694,082 (344)
A Genome-Scale Atlas Reveals Complex Interplay of Transcription and Translation in an Archaeon
mSystems, 2023 The scale of post-transcriptional regulation and the implications of its interplay with other forms of regulation in environmental acclimation are underexplored for organisms of the domain Archaea.
Alan P. R. Lorenzetti +11 more
doaj +1 more source
Nascent RNA sequencing reveals mechanisms of gene regulation in the human malaria parasite Plasmodium falciparum. [PDF]
, 2017 Gene expression in Plasmodium falciparum is tightly regulated to ensure successful propagation of the parasite throughout its complex life cycle. The earliest transcriptomics studies in P.
Batugedara, Gayani +5 more
core +1 more source
BMC Plant Biology, 2021 Seed germination is the process through which a quiescent organ reactivates its metabolism culminating with the resumption cell divisions. It is usually the growth of a plant contained within a seed and results in the formation of a seedling.
Xiaofei Xue +10 more
doaj +1 more source
Cell-type specific analysis of translating RNAs in developing flowers reveals new levels of control [PDF]
, 2010 Determining both the expression levels of mRNA and the regulation of its translation is important in understanding specialized cell functions. In this study, we describe both the expression profiles of cells within spatiotemporal domains of the ...
Elliot M Meyerowitz +4 more
core +2 more sources
Post-transcriptional regulation of microRNA expression [PDF]
RNA, 2006 microRNAs (miRNAs) are endogenous, noncoding ∼22-nucleotide RNA molecules that have recently emerged as fundamental, post-transcriptional regulators of cognate target gene expression. Many mammalian miRNAs are expressed in a tissue-specific manner, a phenomenon that has so far been attributed to transcriptional regulation.
Philipp J.F. Leuschner +3 more
openaire +3 more sources
Biomolecules, 2015 DDX6 (p54/RCK) is a human RNA helicase with central roles in mRNA decay and translation repression. To help our understanding of how DDX6 performs these multiple functions, we conducted the first unbiased, large-scale study to map the DDX6-centric ...
Rebecca Bish +6 more
doaj +1 more source
Connexins: synthesis, post-translational modifications, and trafficking in health and disease [PDF]
, 2018 Connexins are tetraspan transmembrane proteins that form gap junctions and facilitate direct intercellular communication, a critical feature for the development, function, and homeostasis of tissues and organs.
Aasen, Trond +5 more
core +3 more sources
Surveying the global landscape of post-transcriptional regulators [PDF]
Nature Structural & Molecular Biology, 2021 Numerous proteins regulate gene expression by modulating mRNA translation and decay. In order to uncover the full scope of these post-transcriptional regulators, we conducted an unbiased survey that quantifies regulatory activity across the budding yeast proteome and delineates the protein domains responsible for these effects.
Kendra Reynaud +4 more
openaire +4 more sources
Are microRNAs Important Players in HIV-1 Infection? An Update
Viruses, 2018 HIV-1 has already claimed over 35 million human lives globally. No curative treatments are currently available, and the only treatment option for over 36 million people currently living with HIV/AIDS are antiretroviral drugs that disrupt the function of ...
Muthukumar Balasubramaniam +2 more
doaj +1 more source
The Distinctive Regulation of Cyanobacterial Glutamine Synthetase [PDF]
, 2018 Glutamine synthetase (GS) features prominently in bacterial nitrogen assimilation as it catalyzes the entry of bioavailable nitrogen in form of ammonium into cellular metabolism. The classic example, the comprehensively characterized GS of enterobacteria,
Bolay, Paul +3 more
core +1 more source