Results 51 to 60 of about 1,106,411 (391)

Post-transcriptional regulation of proinflammatory proteins [PDF]

open access: yesJournal of Leukocyte Biology, 2004
AbstractPost-transcriptional mechanisms play a critical role in regulating the expression of numerous proteins that promote inflammatory arthritis. The mRNAs encoding a subset of these proteins possess adenine/uridine-rich elements (AREs) in their 3′-untranslated regions that profoundly influence the rate at which mRNA is degraded and translated into ...
Paul A. Anderson   +3 more
openaire   +3 more sources

Sugar Signaling and Post-transcriptional Regulation in Plants: An Overlooked or an Emerging Topic?

open access: yesFrontiers in Plant Science, 2020
Plants are autotrophic organisms that self-produce sugars through photosynthesis. These sugars serve as an energy source, carbon skeletons, and signaling entities throughout plants’ life.
Ming Wang   +8 more
semanticscholar   +1 more source

Post-transcriptional regulation in metabolic diseases [PDF]

open access: yesRNA Biology, 2012
Post-transcriptional gene regulation by microRNAs (miRNAs) and RNA-binding proteins (RBPs) is central to many biological functions. Aberrant gene expression patterns underlie many metabolic diseases that represent major public health concerns and formidable therapeutic challenges.
Wook Kim, Eun Kyung Lee
openaire   +3 more sources

Post-transcriptional regulation of early embryogenesis [PDF]

open access: yesF1000Prime Reports, 2015
Gene expression is controlled by diverse mechanisms before, during, and after transcription. Chromatin modification factors as well as transcriptional repressors, silencers, and enhancers all feed into how eukaryotes transcribe RNA in the nucleus.
openaire   +3 more sources

Target mRNA abundance dilutes microRNA and siRNA activity

open access: yesMolecular Systems Biology, 2010
Post‐transcriptional regulation by microRNAs and siRNAs depends not only on characteristics of individual binding sites in target mRNA molecules, but also on system‐level properties such as overall molecular concentrations.
Aaron Arvey   +4 more
doaj   +1 more source

Functional Role of Non-Coding RNAs during Epithelial-To-Mesenchymal Transition

open access: yesNon-Coding RNA, 2018
Epithelial-to-mesenchymal transition (EMT) is a key biological process involved in a multitude of developmental and pathological events. It is characterized by the progressive loss of cell-to-cell contacts and actin cytoskeletal rearrangements, leading ...
Almudena Expósito-Villén   +2 more
doaj   +1 more source

An update on transcriptional and post-translational regulation of brain voltage-gated sodium channels [PDF]

open access: yes, 2015
Voltage-gated sodium channels are essential proteins in brain physiology, as they generate the sodium currents that initiate neuronal action potentials.
Beltran-Alvarez, Pedro   +1 more
core   +1 more source

Transcription and post-transcriptional regulation of spermatogenesis [PDF]

open access: yesPhilosophical Transactions of the Royal Society B: Biological Sciences, 2010
Spermatogenesis in mammals is achieved by multiple players that pursue a common goal of generating mature spermatozoa. The developmental processes acting on male germ cells that culminate in the production of the functional spermatozoa are regulated at both the transcription and post-transcriptional levels. This review addresses recent progress towards
Anilkumar Bettegowda, Miles F. Wilkinson
openaire   +3 more sources

Involvement of microRNA in Solid Cancer: Role and Regulatory Mechanisms

open access: yesBiomedicines, 2021
MicroRNAs (miRNAs) function as the post-transcriptional factor that finetunes the gene expression by targeting to the specific candidate. Mis-regulated expression of miRNAs consequently disturbs gene expression profile, which serves as the pivotal ...
Ying-Chin Lin   +4 more
doaj   +1 more source

HnRNP-like proteins as post-transcriptional regulators [PDF]

open access: yes, 2014
Plant cells contain a diverse repertoire of RNA-binding proteins (RBPs) that coordinate a network of post-transcriptional regulation. RBPs govern diverse developmental processes by modulating the gene expression of specific transcripts.
Ho, Chai Ling   +2 more
core   +1 more source

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