Results 1 to 10 of about 445,830 (265)
Artificial Intelligence Transforming Post-Translational Modification Research [PDF]
BioengineeringPost-Translational Modifications (PTMs) are covalent changes to amino acids that occur after protein synthesis, including covalent modifications on side chains and peptide backbones.
Doo Nam Kim +8 more
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Post-Translational Modification of WRKY Transcription Factors [PDF]
PlantsPost-translational modifications (PTMs) of proteins are involved in numerous biological processes, including signal transduction, cell cycle regulation, growth and development, and stress responses. WRKY transcription factors (TFs) play significant roles
Xiangui Zhou, Zaojuan Lei, Pengtian An
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Post-Translational Modification of MR Activity [PDF]
, 2019 The mineralocorticoid receptor (MR) is a ligand-activated transcription factor that transduces the effects of aldosterone and glucocorticoids in a tissue- and cell type-specific ways.
Alvarez de la Rosa, Diego +1 more
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Lactylation: The emerging frontier in post-translational modification [PDF]
Frontiers in GeneticsLactate, a metabolic byproduct, has gained recognition as a highly influential signaling molecule. Lactylation, an emerging form of post-translational modification derived from lactate, plays a crucial role in numerous cellular processes such as ...
Zhou Lu +10 more
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The interplay of post-translational modification and gene therapy [PDF]
Drug Design, Development and Therapy, 2016 Victor Chukwudi Osamor,1–3 Shalom N Chinedu,3,4 Dominic E Azuh,3,5 Emeka Joshua Iweala,3,4 Olubanke Olujoke Ogunlana3,4 1Covenant University Bioinformatics Research (CUBRe) Unit, Department of Computer and Information Sciences, College of Science ...
Osamor VC +4 more
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Post-Translational Modification of PTEN Protein: Quantity and Activity [PDF]
Oncology ReviewsPost-translational modifications play crucial roles in regulating protein functions and stabilities. PTEN is a critical tumor suppressor involved in regulating cellular proliferation, survival, and migration processes.
Xiao Li +4 more
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Antioxidants, 2021 Post-translational modifications based on redox reactions “switch on-off” the biological activity of different downstream targets, modifying a myriad of processes and providing an efficient mechanism for signaling regulation in physiological and ...
Mabel Buelna-Chontal +4 more
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FIP200 Methylation by SETD2 Prevents Trim21-Induced Degradation and Preserves Autophagy Initiation
Cells, 2022 FIP200, also known as RB1CC1, is a protein that assembles the autophagy initiation complex. Its post-translational modifications and degradation mechanisms are unclear. Upon autophagy activation, we find that FIP200 is methylated at lysine1133 (K1133) by
Yuan Dai +5 more
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Glycosylation—The Most Diverse Post-Translational Modification
Biomolecules, 2022 This article is part of the Special Issue Glycosylation—The Most Diverse Post-Translational Modification [...]
Erika Staudacher +2 more
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Post-translation modifications [PDF]
Current Opinion in Chemical Biology, 2009 The development of proteomics has been one of the great achievements in analytical chemical biology in the past ten years. The determination of the total protein constituents in biological samples has allowed new and unprecedented insights into cellular processes and diseases.
Lara K. Mahal, Carlito B. Lebrilla
openaire +3 more sources