Results 21 to 30 of about 267,024 (262)
Biosynthesis and functions of sulfur modifications in tRNA
Frontiers in Genetics, 2014 Sulfur is an essential element for a variety of cellular constituents in all living organisms. In tRNA molecules, there are many sulfur-containing nucleosides, such as the derivatives of 2‑thiouridine (s2U), 4-thiouridine (s4U), 2-thiocytidine (s2C), and
Naoki eShigi
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Post-Translational Modification of Lamins: Mechanisms and Functions
Frontiers in Cell and Developmental Biology, 2022 Lamins are the ancient type V intermediate filament proteins contributing to diverse biological functions, such as the maintenance of nuclear morphology, stabilization of chromatin architecture, regulation of cell cycle progression, regulation of spatial-
Mingyue Zheng +2 more
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Post-translational modifications of the polycystin proteins [PDF]
Cellular Signalling, 2020 Autosomal dominant polycystic kidney disease (ADPKD) is the most common inherited cause of kidney failure and affects up to 12 million people worldwide. Germline mutations in two genes, PKD1 or PKD2, account for almost all patients with ADPKD.
Streets, A., Ong, A.
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The post-translational modification landscape of commercial beers
Scientific Reports, 2021 Beer is one of the most popular beverages worldwide. As a product of variable agricultural ingredients and processes, beer has high molecular complexity.
Edward D. Kerr +8 more
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iProteinDB: An Integrative Database of Drosophila Post-translational Modifications
G3: Genes, Genomes, Genetics, 2019 Post-translational modification (PTM) serves as a regulatory mechanism for protein function, influencing their stability, interactions, activity and localization, and is critical in many signaling pathways.
Yanhui Hu +10 more
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Carbon Dioxide and the Carbamate Post-Translational Modification
Frontiers in Molecular Biosciences, 2022 Carbon dioxide is essential for life. It is at the beginning of every life process as a substrate of photosynthesis. It is at the end of every life process as the product of post-mortem decay.
Lynsay I. Blake, Martin J. Cann
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Subcellular trafficking and post-translational modification regulate PIN polarity in plants
Frontiers in Plant Science, 2022 Auxin regulates plant growth and tropism responses. As a phytohormone, auxin is transported between its synthesis sites and action sites. Most natural auxin moves between cells via a polar transport system that is mediated by PIN-FORMED (PIN) auxin ...
Shuyang Cheng +3 more
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BMC Genomics, 2017 Background Post-translational modification (PTM) of proteins is central to many cellular processes across all domains of life, but despite decades of study and a wealth of genomic and proteomic data the biological function of many PTMs remains unknown ...
Colin W. Brown +6 more
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Post-Translational Modifications of Exosomal Proteins
Frontiers in Immunology, 2014 Exosomes mediate intercellular communication and participate in many cell processes such as cancer progression, immune activation or evasion, and the spread of infection. Exosomes are small vesicles secreted to the extracellular environment through the release of intraluminal vesicles contained in multivesicular bodies (MVBs) upon the fusion of these ...
Olga Moreno-Gonzalo +2 more
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Post-Translational Modifications of Extracellular Proteasome [PDF]
Molecules, 2020 The ubiquitin-proteasome system (UPS) is one of the major protein degradation pathways in eukaryotic cells. Abnormal functioning of this system has been observed in cancer and neurological diseases. The 20S proteasomes, essential components of the UPS, are present not only within the cells but also in the extracellular space, and their concentration in
Anna S. Tsimokha +4 more
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