Results 21 to 30 of about 6,398,571 (341)
Post-Translational Modification Networks in Ferroptosis: Orchestrating Defense, Drug Resistance, and Therapeutic Opportunities in Hepatocellular Carcinoma [PDF]
Journal of Hepatocellular CarcinomaJie Chen,* Lingling Li,* Sufang Fang, Haitao Zhou Department of Hepatobiliary & Pancreatic Surgery, The Affiliated Yangming Hospital of Ningbo University (Yuyao People’s Hospital), Ningbo, Zhejiang, People’s Republic of China&ast ...
Chen J, Li L, Fang S, Zhou H
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Journal of Hematology & OncologyNecroptosis represents a distinct form of programmed cell death that exhibits characteristics of both necrosis and apoptosis. Due to its potential to activate anti-cancer immune responses, utilizing necroptosis to enhance immune activity within the tumor
Jinxin Tang +7 more
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Clathrin Heavy Chain Knockdown Impacts CXCR4 Signaling and Post-translational Modification [PDF]
Frontiers in Cell and Developmental Biology, 2019 Recent research has implicated endocytic pathways as important regulators of receptor signaling. However, the role of endocytosis in regulating chemokine CXC receptor 4 (CXCR4) signaling remains largely unknown.
Maxwell S. DeNies +8 more
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Tyrosine Sulfation as a Protein Post-Translational Modification
Molecules, 2015 Integration of inorganic sulfate into biological molecules plays an important role in biological systems and is directly involved in the instigation of diseases.
Yuh-Shyong Yang +5 more
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Antioxidants, 2021 Post-translational modifications based on redox reactions “switch on-off” the biological activity of different downstream targets, modifying a myriad of processes and providing an efficient mechanism for signaling regulation in physiological and ...
Mabel Buelna-Chontal +4 more
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Spin labelling via metabolic glycoengineering for studying post-translational protein modification by electron paramagnetic resonance spectroscopy [PDF]
, 2023 Post-translational modifications are involved in many cellular processes. The addition of O-linked β-N-acetylglucosamine (O-GlcNAc) is a ubiquitous post-translational modification essential for regulatory processes in mammalian cells.
Malte, Drescher +2 more
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FIP200 Methylation by SETD2 Prevents Trim21-Induced Degradation and Preserves Autophagy Initiation
Cells, 2022 FIP200, also known as RB1CC1, is a protein that assembles the autophagy initiation complex. Its post-translational modifications and degradation mechanisms are unclear. Upon autophagy activation, we find that FIP200 is methylated at lysine1133 (K1133) by
Yuan Dai +5 more
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Research progress on post-translational modification of proteins and cardiovascular diseases
Cell Death Discovery, 2023 Cardiovascular diseases (CVDs) such as atherosclerosis, myocardial remodeling, myocardial ischemia-reperfusion (I/R) injury, heart failure, and oxidative stress are among the greatest threats to human health worldwide.
Xue-Qi Cheng +3 more
semanticscholar +1 more source
Uncovering Post-Translational Modification-Associated Protein-Protein Interactions
Current Opinion in Structural Biology, 2022 In living systems, the chemical space and functional repertoire of proteins are dramatically expanded through the post-translational modification (PTM) of various amino acid residues.
Shu Wang +2 more
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Frontiers in Molecular Biosciences, 2022 Glutathione peroxidase 4 (GPX4) is one of the most important antioxidant enzymes. As the key regulator of ferroptosis, GPX4 has attracted considerable attention in the fields of cancer, cardiovascular, and neuroscience research in the past 10 years.
Can Cui, Fei Yang, Qian Li
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