Results 1 to 10 of about 229,666 (114)
MiRNA post-transcriptional modification dynamics in T cell activation [PDF]
iScience, 2021 Summary: T cell activation leads to extensive changes in the miRNA repertoire. Although overall miRNA expression decreases within a few hours of T cell activation, some individual miRNAs are specifically upregulated.
Ana Rodríguez-Galán +6 more
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m1A Post‐Transcriptional Modification in tRNAs [PDF]
Biomolecules, 2017 To date, about 90 post‐transcriptional modifications have been reported in tRNA expanding their chemical and functional diversity. Methylation is the most frequent post‐transcriptional tRNA modification that can occur on almost all nitrogen sites of
Stephanie Oerum +3 more
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Post-Transcriptional Regulation of Viral RNA through Epitranscriptional Modification
Cells, 2021 The field of mRNA modifications has been steadily growing in recent years as technologies have improved and the importance of these residues became clear.
David G. Courtney
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Cell Reports, 2016 MicroRNAs (miRNAs) regulate diverse biological processes by repressing mRNAs, but their modest effects on direct targets, together with their participation in larger regulatory networks, make it challenging to delineate miRNA-mediated effects.
Sara J.C. Gosline +9 more
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Journal of Hematology & OncologyNecroptosis represents a distinct form of programmed cell death that exhibits characteristics of both necrosis and apoptosis. Due to its potential to activate anti-cancer immune responses, utilizing necroptosis to enhance immune activity within the tumor
Jinxin Tang +7 more
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Biomolecules, 2020 Transfer RNAs (tRNAs) are the most heavily modified RNA species in life entities. Post-transcriptional modifications severely impact the structure and function of tRNAs.
Tongmeng Yan +3 more
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Regulatory role of RNA N6-methyladenosine modifications during skeletal muscle development
Frontiers in Cell and Developmental Biology, 2022 Functional cells in embryonic myogenesis and postnatal muscle development undergo multiple stages of proliferation and differentiation, which are strict procedural regulation processes.
Baojun Yu +6 more
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The Potential Role of m6A in the Regulation of TBI-Induced BGA Dysfunction
Antioxidants, 2022 The brain–gut axis (BGA) is an important bidirectional communication pathway for the development, progress and interaction of many diseases between the brain and gut, but the mechanisms remain unclear, especially the post-transcriptional regulation of ...
Peizan Huang +4 more
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Frontiers in Immunology, 2022 BackgroundPancreatic cancer (PC) is one of the most lethal malignancies and carries a dismal mortality and morbidity. Four types of RNA modification (namely m6A, m1A, APA and A-to-I) could be catalyzed by distinct enzymatic compounds (“writers ...
Wenzhe Gao +12 more
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Detecting RNA modification using direct RNA sequencing: A systematic review
Computational and Structural Biotechnology Journal, 2022 Post-transcriptional RNA modifications are involved in a range of important cellular processes, including the regulation of gene expression and fine-tuning of the functions of RNA molecules.
Xichen Zhao +4 more
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