Results 41 to 50 of about 6,379,811 (286)
RNA modification includes four main types, N6‐methyladenosine, N1‐methyladenosine, alternative polyadenylation (APA), and adenosine‐to‐inosine (A‐to‐I) RNA editing, involving 41 enzymes that serve as “writers”, “readers” and “erasers”.
Feng Qi +6 more
doaj +1 more source
Post-transcriptional modifications are very important after all [PDF]
In the beginning there was RNA and our lives as molecular biologists and biochemists proceeded simply.
openaire +2 more sources
Complex transcriptional and post‐transcriptional regulation of an enzyme for lipopolysaccharide modification [PDF]
SummaryThe PhoQ/PhoP two‐component system activates many genes for lipopolysaccharide (LPS) modification when cells are grown at low Mg2+ concentrations. An additional target of PhoQ and PhoP is MgrR, an Hfq‐dependent small RNA that negatively regulates expression of eptB, also encoding a protein that carries out LPS modification.
Kyung, Moon +4 more
openaire +2 more sources
Transcriptional gene silencing mutants in "Arabidopsis thaliana" and their impact on nuclear architecture and heterochromatin organization [PDF]
The epigenetic regulation of gene expression is defined by covalent modifications of DNA and histone tails as well as by chromatin structure and nuclear architecture.
Valeska Probst, Aline
core +1 more source
Multi-faceted regulation of CREB family transcription factors
cAMP response element-binding protein (CREB) is a ubiquitously expressed nuclear transcription factor, which can be constitutively activated regardless of external stimuli or be inducibly activated by external factors such as stressors, hormones ...
Md Arifur Rahman Chowdhury +6 more
doaj +1 more source
Differences in tRNA expression have been implicated in a remarkable number of biological processes. There is growing evidence that tRNA genes can play dramatically different roles depending on both expression and post-transcriptional modification, yet ...
Thalia Salinas-Giegé (8372601) +7 more
core +1 more source
ABSTRACT Purpose To explore caregivers' experiences and perceptions of the nutritional challenges faced by children and adolescents undergoing cancer treatment, including oral intake and the use of nutritional support. Methods This was a qualitative study based on focus groups with parents and caregivers at a Brazilian pediatric oncology hospital ...
Danyelle Apparecida Balsamão Marques +5 more
wiley +1 more source
Transcriptional control: repression by local chromatin modification
It is becoming increasingly clear that chromatin modification plays a fundamental part in transcriptional control. Recent studies provide new insights into how transcriptional repressors, in addition to blocking activators, may recruit repression ...
Ip, Y. Tony, Ashraf, Shovon Imtiaz
core +2 more sources
ABSTRACT Introduction Hyperlipidemia is a major risk factor for atherosclerotic cardiovascular disease (ASCVD). Although statins are the cornerstone of lipid‐lowering therapy, their use may be limited in some patients by adverse effects. This study evaluated the possible impact of non‐drug treatment using double‐filtration plasmapheresis (DFPP) on CD14+
Yun Cheng +3 more
wiley +1 more source
The essential role of YAP O-GlcNAcylation in high-glucose-stimulated liver tumorigenesis
Yap is a transcriptional factor involved in tumorigenesis. Here the authors show that a previously unknown post-translational modification of Yap, O-GlcNAcylation, increases its transcriptional activity and is required for high glucose-induced liver ...
Xiao Zhang +12 more
doaj +1 more source

