Results 101 to 110 of about 6,398,571 (341)
Post-Translational Tyrosine Geranylation in Cyanobactin Biosynthesis
, 2018 Prenylation is a widespread modification that improves the biological activities of secondary metabolites. This reaction also represents a key modification step in biosyntheses of cyanobactins, a family of ribosomally synthesized and post-translationally
Yue Hao (1261215) +7 more
core +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Regulation of post-translational modification in breast cancer treatment
BMB Reports, 2019 The small ubiquitin-related modification molecule (SUMO), one of the post-translational modification molecules, is involved in a variety of cellular functions where it regulates protein activity and stability, transcription, and cell cycling.
Kyung-Sun Heo
semanticscholar +1 more source
Editorial: Bacterial Post-translational Modifications
Frontiers in Microbiology, 2022 International ...
Valerie J. Carabetta +2 more
openaire +5 more sources
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Post-translational Modification-Based Regulation of HIV Replication
Frontiers in Microbiology, 2018 Human immunodeficiency virus (HIV) relies heavily on the host cellular machinery for production of viral progeny. To exploit cellular proteins for replication and to overcome host factors with antiviral activity, HIV has evolved a set of regulatory and ...
Lin Chen +2 more
doaj +1 more source
Diagnostics, 2023 The present review aims to describe the state of the art of research studies investigating the citrullination post-translational modification in adult and pediatric brain tumors.
Diana Valeria Rossetti +4 more
doaj +1 more source
iPTMnet: an integrated resource for protein post-translational modification network discovery
Nucleic Acids Res., 2017 Protein post-translational modifications (PTMs) play a pivotal role in numerous biological processes by modulating regulation of protein function. We have developed iPTMnet (http://proteininformationresource.org/iPTMnet) for PTM knowledge discovery ...
Hong-Zhan Huang +9 more
semanticscholar +1 more source
Analysis of variation site in post-translational modification [PDF]
, 2013 Post-translational modification (PTM) is a modification of a protein after its translation. This modification can occur either by the covalent addition of particular chemical groups or by enzymatic cleavage of peptide bond.
GIRMA, ETSEHIWOT
core
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source