Results 111 to 120 of about 445,929 (364)
Molecular Oncology, EarlyView.Circulating tumor DNA (ctDNA) offers a possibility for different applications in early and late stage breast cancer management. In early breast cancer tumor informed approaches are increasingly used for detecting molecular residual disease (MRD) and early recurrence. In advanced stage, ctDNA provides a possibility for monitoring disease progression and
Eva Valentina Klocker +14 more
wiley +1 more source
Phase Transitions of Plan Modification in Conformant Planning [PDF]
arXiv, 2010 We explore phase transitions of plan modification, which mainly focus on the conformant planning problems. By analyzing features of plan modification in conformant planning problems, quantitative results are obtained. If the number of operators is less than, almost all conformant planning problems can't be solved with plan modification.
arxiv
Multiple mechanisms of growth hormone-regulated gene transcription [PDF]
, 2007 Diverse physiological actions of growth hormone (GH) are mediated by changes in gene transcription. Transcription can be regulated at several levels, including post-translational modification of transcription factors, and formation of multiprotein ...
Calinescu, Anda Alexandra +8 more
core +1 more source
RanBP2-Mediated SUMOylation Promotes Human DNA Polymerase Lambda Nuclear Localization and DNA Repair [PDF]
, 2020 Cellular DNA is under constant attack by a wide variety of agents, both endogenous and exogenous. To counteract DNA damage, human cells have a large collection of DNA repair factors. Among them, DNA polymerase lambda (Polλ) stands out for its versatility,
Cortés Ledesma, Felipe +4 more
core +1 more source
Circulating tumor cells: advancing personalized therapy in small cell lung cancer patients
Molecular Oncology, EarlyView.Small cell lung cancer (SCLC) is an aggressive form of lung cancer that spreads rapidly to secondary sites such as the brain and liver. Cancer cells circulating in the blood, “circulating tumor cells” (CTCs), have demonstrated prognostic value in SCLC, and evaluating biomarkers on CTCs could guide treatment decisions such as for PARP inhibitors ...
Prajwol Shrestha +6 more
wiley +1 more source
Hematology Reports, 2011 In this study, we have examined the role of post-translational modification of the myeloid master regulator C/EBP by small ubiquitin-related modifier (SUMO).
William Hankey +5 more
doaj +1 more source
Post-Translational Modification and Natural Mutation of TRPC Channels
Cells, 2020 Transient Receptor Potential Canonical (TRPC) channels are homologues of Drosophila TRP channel first cloned in mammalian cells. TRPC family consists of seven members which are nonselective cation channels with a high Ca2+ permeability and are activated ...
Xianji Liu +2 more
doaj +1 more source
Post-translational modification of LipL32 during Leptospira interrogans infection. [PDF]
PLoS Neglected Tropical Diseases, 2014 BACKGROUND:Leptospirosis, a re-emerging disease of global importance caused by pathogenic Leptospira spp., is considered the world's most widespread zoonotic disease.
Timothy D Witchell +8 more
doaj +1 more source
Modifications of Simon text model [PDF]
arXiv, 2020 We discuss probability text models and their modifications. We construct processes of different and unique words in a text. The models are to correspond to the real text statistics. The infinite urn model (Karlin model) and the Simon model are the most known models of texts, but they do not give the ability to simulate the number of unique words ...
arxiv
Chemical modification of silicene [PDF]
, 2015 Silicene is a two-dimensional material, which is composed of a single layer of silicon atoms with sp2-sp3 mixed hybridization. The sp2-sp3 mixed hybridization renders silicene excellent reactive ability, facilitating the chemical modification of silicene.
arxiv +1 more source