Results 11 to 20 of about 468,229 (335)

Artificial Intelligence Transforming Post-Translational Modification Research [PDF]

Bioengineering
Post-Translational Modifications (PTMs) are covalent changes to amino acids that occur after protein synthesis, including covalent modifications on side chains and peptide backbones.
Doo Nam Kim, Tianzhixi Yin, Tong Zhang, Alexandria K. Im, John R. Cort, Jordan C. Rozum, David Pollock, Wei-Jun Qian, Song Feng   +8 more
doaj   +2 more sources

Post-Translational Modification of WRKY Transcription Factors [PDF]

Plants
Post-translational modifications (PTMs) of proteins are involved in numerous biological processes, including signal transduction, cell cycle regulation, growth and development, and stress responses. WRKY transcription factors (TFs) play significant roles
Xiangui Zhou, Zaojuan Lei, Pengtian An
doaj   +2 more sources

Structure and post-translational modification of the prostaglandin transporter. [PDF]

Commun Biol
Yu P, Orlando MA, Orlando BJ.
europepmc   +3 more sources

Lactylation: The emerging frontier in post-translational modification [PDF]

Frontiers in Genetics
Lactate, a metabolic byproduct, has gained recognition as a highly influential signaling molecule. Lactylation, an emerging form of post-translational modification derived from lactate, plays a crucial role in numerous cellular processes such as ...
Zhou Lu, Xueting Zheng, Mingsong Shi, Yuan Yin, Yuanyuan Liang, Zhiyan Zou, Chenghe Ding, Yuanjing He, Yan Zhou, Xiaoan Li, Xiaoan Li   +10 more
doaj   +2 more sources

Implications of Oxidative and Nitrosative Post-Translational Modifications in Therapeutic Strategies against Reperfusion Damage

Antioxidants, 2021
Post-translational modifications based on redox reactions “switch on-off” the biological activity of different downstream targets, modifying a myriad of processes and providing an efficient mechanism for signaling regulation in physiological and ...
Mabel Buelna-Chontal, Wylly R. García-Niño, Alejandro Silva-Palacios, Cristina Enríquez-Cortina, Cecilia Zazueta   +4 more
doaj   +1 more source

FIP200 Methylation by SETD2 Prevents Trim21-Induced Degradation and Preserves Autophagy Initiation

Cells, 2022
FIP200, also known as RB1CC1, is a protein that assembles the autophagy initiation complex. Its post-translational modifications and degradation mechanisms are unclear. Upon autophagy activation, we find that FIP200 is methylated at lysine1133 (K1133) by
Yuan Dai, Weijia Luo, Wenjiao Li, Zhishi Chen, Xinjie Wang, Jiang Chang   +5 more
doaj   +1 more source

Post-translation modifications [PDF]

Current Opinion in Chemical Biology, 2009
The development of proteomics has been one of the great achievements in analytical chemical biology in the past ten years. The determination of the total protein constituents in biological samples has allowed new and unprecedented insights into cellular processes and diseases.
Carlito B, Lebrilla, Lara K, Mahal
openaire   +2 more sources

Glycosylation—The Most Diverse Post-Translational Modification

Biomolecules, 2022
This article is part of the Special Issue Glycosylation—The Most Diverse Post-Translational Modification [...]
Erika Staudacher, Els J. M. Van Damme, Guy Smagghe   +2 more
doaj   +1 more source

Deciphering post‐translational modification codes [PDF]

FEBS Letters, 2013
Post‐translational modifications (PTMs) occur on nearly all proteins. Many domains within proteins are modified on multiple amino acid sidechains by diverse enzymes to create a myriad of possible protein species. How these combinations of PTMs lead to distinct biological outcomes is only beginning to be understood.
Lothrop, Adam P., Torres, Matthew P., Fuchs, Stephen M.   +2 more
openaire   +2 more sources

Post-Translational Modifications of ATG4B in the Regulation of Autophagy

Cells, 2022
Autophagy plays a key role in eliminating and recycling cellular components in response to stress, including starvation. Dysregulation of autophagy is observed in various diseases, including neurodegenerative diseases, cancer, and diabetes.
Na Yeon Park, Doo Sin Jo, Dong-Hyung Cho
doaj   +1 more source