Results 11 to 20 of about 456,947 (289)

Post-Translational Modifications of ATG4B in the Regulation of Autophagy

open access: yesCells, 2022
Autophagy plays a key role in eliminating and recycling cellular components in response to stress, including starvation. Dysregulation of autophagy is observed in various diseases, including neurodegenerative diseases, cancer, and diabetes.
Na Yeon Park, Doo Sin Jo, Dong-Hyung Cho
doaj   +1 more source

A novel synthetic chemistry approach to linkage-specific ubiquitin conjugation. [PDF]

open access: yes, 2015
Ubiquitination is of great importance as the post-translational modification of proteins with ubiquitin, or ubiquitin chains, facilitates a number of vital cellular processes.
Caddick, S   +4 more
core   +1 more source

A convolutional neural network based tool for predicting protein AMPylation sites from binary profile representation

open access: yesScientific Reports, 2022
AMPylation is an emerging post-translational modification that occurs on the hydroxyl group of threonine, serine, or tyrosine via a phosphodiester bond. AMPylators catalyze this process as covalent attachment of adenosine monophosphate to the amino acid ...
Sayed Mehedi Azim   +4 more
doaj   +1 more source

Potential protein post-translational modification in ERp57: A phenotype marker for male fertility

open access: yesJournal of Human Reproductive Sciences, 2010
Background : In protein expression, post-translational modification is an important process. It is also an important process in human reproductive science. ERp57 is a molecule that is mentioned for post-translational modification. ERp57 is a component of
Viroj Wiwanitkit
doaj   +1 more source

Analysis of a macrophage carbamylated proteome reveals a function in post-translational modification crosstalk

open access: yesCell Communication and Signaling, 2023
Background Lysine carbamylation is a biomarker of rheumatoid arthritis and kidney diseases. However, its cellular function is understudied due to the lack of tools for systematic analysis of this post-translational modification (PTM).
Youngki You   +9 more
doaj   +1 more source

Subcellular trafficking and post-translational modification regulate PIN polarity in plants

open access: yesFrontiers in Plant Science, 2022
Auxin regulates plant growth and tropism responses. As a phytohormone, auxin is transported between its synthesis sites and action sites. Most natural auxin moves between cells via a polar transport system that is mediated by PIN-FORMED (PIN) auxin ...
Shuyang Cheng   +3 more
doaj   +1 more source

Redox signaling, Nox5 and vascular remodeling in hypertension [PDF]

open access: yes, 2015
Purpose of review: Extensive data indicate a role for reactive oxygen species (ROS) and redox signaling in vascular damage in hypertension. However, molecular mechanisms underlying these processes remain unclear, but oxidative post-translational ...
De Lucca Camargo, Livia   +5 more
core   +1 more source

Post-Translational Modification of Lamins: Mechanisms and Functions

open access: yesFrontiers in Cell and Developmental Biology, 2022
Lamins are the ancient type V intermediate filament proteins contributing to diverse biological functions, such as the maintenance of nuclear morphology, stabilization of chromatin architecture, regulation of cell cycle progression, regulation of spatial-
Mingyue Zheng   +2 more
doaj   +1 more source

The rational parameterisation theorem for multisite post-translational modification systems [PDF]

open access: yes, 2009
Post-translational modification of proteins plays a central role in cellular regulation but its study has been hampered by the exponential increase in substrate modification forms (“modforms”) with increasing numbers of sites.
Gunawardena, Jeremy, Thomson, Matthew
core   +1 more source

The post-translational modification landscape of commercial beers

open access: yesScientific Reports, 2021
Beer is one of the most popular beverages worldwide. As a product of variable agricultural ingredients and processes, beer has high molecular complexity.
Edward D. Kerr   +8 more
doaj   +1 more source

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