Post-translational modification crosstalk in acute pancreatitis: linking acinar stress to innate immune amplification and tissue repair. [PDF]
Front ImmunolChen M, An P, Jing S, Wu L, Wang R.
europepmc +1 more source
Endothelial Cell Proteins as Biomarkers in Susac Syndrome
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Susac syndrome (SS) is a rare CD8+ T cell–mediated microangiopathy affecting the brain, retina, and auditory labyrinth. Endothelial injury is thought to be a central mechanism; however, no circulating disease biomarkers are known. We performed targeted proteomic profiling to identify circulating endothelial‐associated proteins as ...
Rohit Benjamin +11 more
wiley +1 more source
Data‐Driven SuStaIn Model of Disability Progression in Amyotrophic Lateral Sclerosis
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To determine whether ordinal Subtype and Stage Inference (SuStaIn) applied to routine ALSFRS‐R item scores can identify reproducible disability progression patterns in amyotrophic lateral sclerosis (ALS) and provide clinically meaningful staging.
Giammarco Milella +5 more
wiley +1 more source
Toward Rational Design of Precision-Fermented Milk Proteins: Integrating Cross-Species Selection, Post-Translational Modification, and AI Optimization. [PDF]
Compr Rev Food Sci Food SafGuo Z +6 more
europepmc +1 more source
Session 28: Post-Translational Modifications-Other Post-Translational Modifications
Molecular & Cellular Proteomics, 2005 openaire +1 more source
Diffusion Basis Spectrum Imaging of Tissue Microstructure and Early Treatment in Multiple Sclerosis
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Conventional MRI cannot resolve the coexisting pathological processes within multiple sclerosis tissue. Diffusion Basis Spectrum Imaging decomposes the diffusion signal into fiber, cell, and hindered ratios indexing axonal integrity, cellularity, and extracellular space, respectively.
Apisit Kaewsanit +10 more
wiley +1 more source
Rapid Histone Post-Translational Modification Analysis Using Alternative Proteases and Tandem Mass Tags. [PDF]
Anal ChemTurner NP +6 more
europepmc +1 more source
Post-translational modifications may affect a protein’s localization, half-life or structural conformation. Palmitoylation is the only re- versible lipid modification known to date.
Denhardt-Eriksson, Robin Alexander +4 more
core
The Association of Amyloid‐β and Tau With Synaptic Dysfunction in Alzheimer's Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To clarify the relative contributions of amyloid and tau to synaptic dysfunction in Alzheimer's disease (AD). Methods We included 109 cognitively unimpaired and impaired individuals from the Geneva Memory Center with available CSF synaptic biomarkers (neurogranin, SNAP‐25, GAP‐43). Participants were stratified according to amyloid (A)
Fausto Roveta +11 more
wiley +1 more source
Site-specific post-translational modification detection by polar charged engineered MspA nanopores. [PDF]
Chem SciLin S +6 more
europepmc +1 more source