Results 21 to 30 of about 456,947 (289)

Carbon Dioxide and the Carbamate Post-Translational Modification

open access: yesFrontiers in Molecular Biosciences, 2022
Carbon dioxide is essential for life. It is at the beginning of every life process as a substrate of photosynthesis. It is at the end of every life process as the product of post-mortem decay.
Lynsay I. Blake, Martin J. Cann
doaj   +1 more source

SLoMo: automated site localization of modifications from ETD/ECD mass spectra [PDF]

open access: yes, 2009
Recently, software has become available to automate localization of phosphorylation sites from CID data and to assign associated confidence scores. We present an algorithm, SLoMo (Site Localization of Modifications), which extends this capability to ETD ...
Bailey, Christopher M   +5 more
core   +1 more source

Interplay between R513 methylation and S516 phosphorylation of the cardiac voltage-gated sodium channel [PDF]

open access: yes, 2014
Arginine methylation is a novel post-translational modification within the voltage-gated ion channel superfamily, including the cardiac sodium channel, Naᵥ1.5.
Beltran-Alvarez, Pedro   +5 more
core   +1 more source

Biosynthesis and functions of sulfur modifications in tRNA

open access: yesFrontiers in Genetics, 2014
Sulfur is an essential element for a variety of cellular constituents in all living organisms. In tRNA molecules, there are many sulfur-containing nucleosides, such as the derivatives of 2‑thiouridine (s2U), 4-thiouridine (s4U), 2-thiocytidine (s2C), and
Naoki eShigi
doaj   +1 more source

Regulation of Lignin Biosynthesis by Post-translational Protein Modifications

open access: yesFrontiers in Plant Science, 2020
Post-translational modification of proteins exerts essential roles in many biological processes in plants. The function of these chemical modifications has been extensively characterized in many physiological processes, but how these modifications ...
Daniel B. Sulis, Jack P. Wang
doaj   +1 more source

Role of glutathionylation in infection and inflammation [PDF]

open access: yes, 2019
Glutathionylation, that is, the formation of mixed disulfides between protein cysteines and glutathione (GSH) cysteines, is a reversible post-translational modification catalyzed by dierent cellular oxidoreductases, by which the redox state of the cell
Baldelli, S.   +5 more
core   +1 more source

Large-scale analysis of post-translational modifications in E. coli under glucose-limiting conditions

open access: yesBMC Genomics, 2017
Background Post-translational modification (PTM) of proteins is central to many cellular processes across all domains of life, but despite decades of study and a wealth of genomic and proteomic data the biological function of many PTMs remains unknown ...
Colin W. Brown   +6 more
doaj   +1 more source

Identification of N-terminal protein acetylation and arginine methylation of the voltage-gated sodium channel in end-stage heart failure human heart [PDF]

open access: yes, 2014
The α subunit of the cardiac voltage-gated sodium channel, Naᵥ1.5, provides the rapid sodium inward current that initiates cardiomyocyte action potentials.
Batlle, Montserrat   +13 more
core   +1 more source

The interplay of post-translational modification and gene therapy [PDF]

open access: yes, 2016
Several proteins interact either to activate or repress the expression of other genes during transcription. Based on the impact of these activities, the proteins can be classified into readers, modifier writers, and modifier erasers depending on ...
Azuh, Dominic E.   +4 more
core   +2 more sources

Smc5/6: a link between DNA repair and unidirectional replication? [PDF]

open access: yes, 2008
Of the three structural maintenance of chromosome (SMC) complexes, two directly regulate chromosome dynamics. The third, Smc5/6, functions mainly in homologous recombination and in completing DNA replication.
A Losada   +46 more
core   +1 more source

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