Results 21 to 30 of about 625,558 (252)
Post-Translational Modifications of ATG4B in the Regulation of Autophagy
Cells, 2022 Autophagy plays a key role in eliminating and recycling cellular components in response to stress, including starvation. Dysregulation of autophagy is observed in various diseases, including neurodegenerative diseases, cancer, and diabetes.
Na Yeon Park, Doo Sin Jo, Dong-Hyung Cho
doaj +1 more source
Near atmospheric carbon dioxide activates plant ubiquitin cross-linking
BBA Advances, 2023 Background Identifying CO2-binding proteins is vital for our knowledge of CO2-regulated molecular processes. The carbamate post-translational modification is a reversible CO2-mediated adduct that can form on neutral N-terminal α-amino or lysine ε-amino ...
Harry G Gannon, Martin J Cann
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Nucleic Acids Res., 2020 MusiteDeep is an online resource providing a deep-learning framework for protein post-translational modification (PTM) site prediction and visualization. The predictor only uses protein sequences as input and no complex features are needed, which results
Duolin Wang +7 more
semanticscholar +1 more source
Sirtuin Oxidative Post-translational Modifications [PDF]
Frontiers in Physiology, 2021 Increased sirtuin deacylase activity is correlated with increased lifespan and healthspan in eukaryotes. Conversely, decreased sirtuin deacylase activity is correlated with increased susceptibility to aging-related diseases. However, the mechanisms leading to decreased sirtuin activity during aging are poorly understood.
Kelsey S. Kalous +2 more
openaire +3 more sources
Immunological Significance of HMGB1 Post-Translational Modification and Redox Biology
Frontiers in Immunology, 2020 Most extracellular proteins are secreted via the classical endoplasmic reticulum (ER)/Golgi-dependent secretion pathway; however, some proteins, including a few danger-associated molecular patterns (DAMPs), are secreted via non-classical ER/Golgi ...
M. Kwak +5 more
semanticscholar +1 more source
Editorial: Bacterial Post-translational Modifications
Frontiers in Microbiology, 2022 International ...
Valerie J. Carabetta +2 more
openaire +5 more sources
A novel synthetic chemistry approach to linkage-specific ubiquitin conjugation. [PDF]
, 2015 Ubiquitination is of great importance as the post-translational modification of proteins with ubiquitin, or ubiquitin chains, facilitates a number of vital cellular processes.
Caddick, S +4 more
core +1 more source
Scientific Reports, 2022 AMPylation is an emerging post-translational modification that occurs on the hydroxyl group of threonine, serine, or tyrosine via a phosphodiester bond. AMPylators catalyze this process as covalent attachment of adenosine monophosphate to the amino acid ...
Sayed Mehedi Azim +4 more
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Cell Communication and Signaling, 2023 Background Lysine carbamylation is a biomarker of rheumatoid arthritis and kidney diseases. However, its cellular function is understudied due to the lack of tools for systematic analysis of this post-translational modification (PTM).
Youngki You +9 more
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Post-translational Modification Regulates Formation and Cargo-Loading of Extracellular Vesicles
Frontiers in Immunology, 2020 Accumulating evidence suggests that post-translational modifications (PTMs) regulate the selective encapsulation of non-coding RNA molecules into extracellular vesicles (EVs) and contribute to the downstream functions of EVs or EV-cargo non-coding RNAs ...
Jonathan M. Carnino, K. Ni, Yang Jin
semanticscholar +1 more source