Bibliometrics and potential gene analysis of post-translational modifications in lung cancer. [PDF]
J Thorac DisXu H, Ma Y.
europepmc +1 more source
Cas9 Protein Post-translational Modifications (PTMs): A Potential Biomarker of Gene-editing
, 2019 Joshua D. Podlevsky
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Networking of predicted post-translational modification (PTM) sites in human EGFR [PDF]
, 2019 A.U. Malik +3 more
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Cas9 beyond CRISPR – SUMOylation, effector‐like potential and pathogenic adaptation
The FEBS Journal, EarlyView.This Viewpoint explores the possibility that Cas9, beyond its canonical role in CRISPR immunity, may act as a host‐modulating effector during infection by Cas9‐encoding bacteria. Such a nucleomodulin‐like function could be influenced by eukaryotic post‐translational modifications, particularly SUMOylation, with potential implications for host–pathogen ...
Umut Sahin
wiley +1 more source
Intrinsic specificity of a ‘core’ TIP60 acetyltransferase complex in Drosophila
The FEBS Journal, EarlyView.The intrinsic substrate selectivity of the Drosophila TIP60‐core acetyltransferase was determined using synthetic nucleosome arrays. Targeted mass spectrometry revealed site‐specific acetylation of histones H2A, H2A.V, and H4, uncovering distinct acetylation rates and patterns across individual lysines.
Silke Krause +5 more
wiley +1 more source
Post-Translational Modifications in Respiratory Virus Infection: Recent Insights into the Development of In Vitro Models. [PDF]
Int J Mol SciBen Khlifa E +9 more
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Autoimmunity and Periodontitis
Journal of Periodontal Research, EarlyView.In a microbe‐driven inflammatory environment, peptidyl‐arginine deiminase (PAD) enzymes from neutrophils and Porphyromonas gingivalis citrullinate both microbial and self‐antigens. B cell presentation of citrullinated or self‐mimicking epitopes activates T cells that assist B cells in antibody isotype switching, affinity maturation, epitope spreading ...
Massimo Costalonga +2 more
wiley +1 more source
PMADS: an integrated database of curated and proteomics-inferred associations between protein post-translational modifications and drug sensitivity. [PDF]
Nucleic Acids ResZheng J +10 more
europepmc +1 more source
A novel single‐cell NAD‐ME C4 subtype integrated with CAM and bicarbonate use in an aquatic plant
New Phytologist, EarlyView.Summary Many plants maximize photosynthesis by using a CO2‐concentrating mechanism (CCM). Based on physiology, the freshwater plant Ottelia alismoides has three CCMs: C4 metabolism (NAD‐malic enzyme (NAD‐ME) subtype) and bicarbonate‐use during the day plus crassulacean acid metabolism (CAM) at night and lacks Kranz anatomy. Here, we combined a range of
Hong Sheng Jiang +11 more
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Novel protein acylations in ferroptosis: decoding the regulatory roles of lactylation, crotonylation, succinylation, and β-hydroxybutyrylation. [PDF]
Front PharmacolWei M, Wei S, Xie X, Liu T, Deng J.
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