Comparative Proteomics of Salinity Stress Responses in Fish and Aquatic Invertebrates
PROTEOMICS, EarlyView.ABSTRACT Fluctuating salinity is symptomatic of climate change challenging aquatic species. The melting of polar ice, rising sea levels, coastal surface and groundwater salinization, and increased evaporation in arid habitats alter salinity worldwide. Moreover, the frequency and intensity of extreme weather events such as rainstorms and floods increase,
Maxime Leprêtre +3 more
wiley +1 more source
PeaTMOSS: A Dataset and Initial Analysis of Pre-Trained Models in Open-Source Software [PDF]
arXivThe development and training of deep learning models have become increasingly costly and complex. Consequently, software engineers are adopting pre-trained models (PTMs) for their downstream applications. The dynamics of the PTM supply chain remain largely unexplored, signaling a clear need for structured datasets that document not only the metadata ...
arxiv
Investigation of the Urinary Peptidome to Unravel Collagen Degradation in Health and Kidney Disease
PROTEOMICS, EarlyView.ABSTRACT Naturally occurring fragments of collagen type I alpha 1 chain (COL1A1) have been previously associated with chronic kidney disease (CKD), with some fragments showing positive and others negative associations. Using urinary peptidome data from healthy individuals (n = 1131) and CKD patients (n = 5585) this aspect was investigated in detail ...
Ioanna K. Mina +7 more
wiley +1 more source
Profile of urinary amino acids and their post-translational modifications (PTM) including advanced glycation end-products (AGEs) of lysine, arginine and cysteine in lean and obese ZSF1 rats [PDF]
, 2021 Svetlana Baskal +6 more
openalex +1 more source
PROTEOMICS, EarlyView.ABSTRACT Colorectal cancer (CRC) development is closely associated with the accumulation of both genetic and epigenetic alterations. Many efforts have been made to investigate the role of epigenetic modifications in CRC metastasis. In this work, we present the quantitative top‐down proteomics study focusing on histone proteoforms between metastatic ...
Fei Fang +5 more
wiley +1 more source
Challenges of Using Pre-trained Models: the Practitioners' Perspective [PDF]
arXivThe challenges associated with using pre-trained models (PTMs) have not been specifically investigated, which hampers their effective utilization. To address this knowledge gap, we collected and analyzed a dataset of 5,896 PTM-related questions on Stack Overflow. We first analyze the popularity and difficulty trends of PTM-related questions.
arxiv
Overview of Capillary Electrophoresis Analysis of Alkaline Phosphatase (ALP) with Emphasis on Post-Translational Modifications (PTMs) [PDF]
, 2023 Thanih Balbaied, Eric Moore
openalex +1 more source
A thesis submitted in fulfilment of the examination requirements by Charlotte Neal.
openaire +2 more sources
Proteins: Structure, Function, and Bioinformatics, EarlyView.ABSTRACT The SARS‐CoV‐2 nucleocapsid protein, or N‐protein, is a structural protein that plays an important role in the SARS‐CoV‐2 life cycle. The N‐protein takes part in the regulation of viral RNA replication and drives highly specific packaging of full‐length genomic RNA prior to virion formation.
Stefan Loonen +3 more
wiley +1 more source
How do Pre-Trained Models Support Software Engineering? An Empirical Study in Hugging Face [PDF]
arXivOpen-Source Pre-Trained Models (PTMs) provide extensive resources for various Machine Learning (ML) tasks, yet these resources lack a classification tailored to Software Engineering (SE) needs. To address this gap, we derive a taxonomy encompassing 147 SE tasks and apply an SE-oriented classification to PTMs in a popular open-source ML repository ...
arxiv