Results 201 to 210 of about 43,191 (287)

Beads-free protein immunoprecipitation for a mass spectrometry-based interactome and posttranslational modifications analysis [PDF]

, 2015

core   +1 more source

Redox Regulation and Oxidative Stress in Health and Disease: Mechanisms and Therapeutic Targeting

MedComm – Future Medicine, Volume 5, Issue 2, June 2026.
Reactive species serve crucial roles which are tightly regulated in both physiological as well as disease states. At physiological levels, these species are integral to redox signaling, while uncontrolled redox promotes disease pathology. This review examines the dysregulation of these processes.
Mohammad Hossein Azadi, Azadeh Niknejad, Elaheh Amini   +2 more
wiley   +1 more source

Recombinant monoclonal antibodies for labeling tubulin post-translational modifications in <i>Caenorhabditis elegans</i>. [PDF]

MicroPubl Biol
Dobossy L, Wang J, Verhey KJ, Barr M.
europepmc   +1 more source

The Dual Role of Autophagy in Cancer: Mechanisms and Therapeutic Strategies

MedComm – Oncology, Volume 5, Issue 2, June 2026.
Autophagy is a conserved cellular process degrading dysfunctional organelles and protein aggregates to maintain cell homeostasis, and it exhibits context‐dependent duality in cancer. Autophagy functions as a critical tumor‐suppressive mechanism by preventing DNA damage and mutation during tumor initiation.
Xiang‐Zheng Gao, Yuheng Qin, Haoyu Wan, Guang Lu, Han‐Ming Shen   +4 more
wiley   +1 more source

Fenofibrate potentiates the therapeutic efficacy of EZH2 inhibitors on melanoma via TRIM21‐ and OTUD4‐mediated EZH2 ubiquitination

British Journal of Pharmacology, Volume 183, Issue 11, Page 2675-2694, June 2026.
Background and Purpose EZH2 (enhancer of zeste homologue 2) inhibitors are an emerging class of drugs that target epigenetic regulation. However, their efficacy in solid tumours has been limited, partly due to drug‐induced upregulation of fatty acid synthesis.
Rui Cheng, Yuanjun Tang, Xuedi Cao, Xiaotong Yu, Zhanya Huang, Yunyun Guo, Renjing Jin, Yan Wang, Yang Liu, Lixiang Xue, Yuqing Wang   +10 more
wiley   +1 more source

Precision Profiling of the Cardiovascular Post-Translationally Modified Proteome. [PDF]

J Cardiovasc Dev Dis
Pruktanakul T, Theofilatos K.
europepmc   +1 more source

Metal Ion Binding of Vimentin Tail Domain Fragments

ChemBioChem, Volume 27, Issue 9, 14 May 2026.
An investigation of the structural and metal‐binding properties of the isolated vimentin tail domain was performed. The affinity and location of Cu(II) binding to both peptide and protein fragments of the tail domain of vimentin were characterized, providing a foundation for exploring how metals drive conformational change in vimentin intermediate ...
Estely J. Carranza, Marie C. Heffern, Dylan T. Murray   +2 more
wiley   +1 more source

Live-cell decoding of labile post-translational modifications in APE1 with a rationally engineered nano-catcher. [PDF]

Nucleic Acids Res
Zhang R, Xie H, Zhu C, Sun Y, Li K, Li H, Niu X, Jin C, Zhao M.   +8 more
europepmc   +1 more source

Detection of Diagnostic Antibodies in Immune‐Mediated Diseases: A Focus on Antigens and Technologies

ChemBioChem, Volume 27, Issue 9, 14 May 2026.
This review explores autoantibody detection in immune‐mediated diseases, highlighting autoantigens including post‐translational modifications. We compared enzyme‐linked immunosorbent assay and indirect immunofluorescence with automated chemiluminescence platforms.
Silvia Bracci, Feliciana Real‐Fernandez, Federico Pratesi, Francesca Nuti, Paolo Rovero, Anna Maria Papini   +5 more
wiley   +1 more source

Dysregulated post‑translational modifications in granulosa cells drive ovarian dysfunction and potential infertility applications (Review). [PDF]

Int J Mol Med
Zhong Y, Zou Y, Yang Z, Wang J, Pan Z, Feng J.   +5 more
europepmc   +1 more source